澳大利亚对血栓栓塞性疾病风险增加患者使用可回收下腔静脉滤器的经验。
An Australian experience of retrievable inferior vena cava filters in patients with increased risk of thromboembolic disease.
作者信息
McKenzie S, Gibbs H, Leggett D, de Villiers L, Neels M, Redmond K, Harper J
机构信息
Departments of Vascular and Interventional Radiology and Vascular Medicine, Princess Alexandra Hospital, Brisbane, Queensland Australia.
出版信息
Int Angiol. 2010 Feb;29(1):53-7.
AIM
Pulmonary embolism (PE) is a common cause of death and morbidity. Anticoagulant therapy reduces the risk of PE but is associated with bleeding. Inferior vena caval (IVC) filters protect against PE but have an increased long term risk of deep vein thrombosis (DVT). Temporary IVC filters allow protection against PE during high risk situations and may be later removed avoiding the need for long term anticoagulation.
METHODS
We present our experience with the Recovery (Bard, Tempe, AZ) and Tulip (Cook, Bloomington, IN) optionally retrievable filters.
RESULTS
Retrievable filters were planned for 121 patients. Mean age: 58.8 years; 72 male. The indications included: Established venous thromboembolism (VTE) and contraindication to anticoagulation; high risk of VTE and need for surgery with high risk of bleeding; VTE extension despite anti-coagulation. A retrievable filter was placed without significant incident in 113 patients. There were two proven cases of PE. In total there were 27 deaths of patients during the period of their follow up. There was 1 death related to confirmed filter migration. There was 1 sudden unexplained death in a patient with suspected malignancy. Filter removal was attempted in 58 cases at a mean of 44 days and was performed successfully in 52. Thromboembolus was found in the retrieved filter in 30 cases but did not prevent removal in 29.
CONCLUSION
Retrievable IVC Filters are safe and effective in preventing PE in high risk patients. We have demonstrated success in retrieving filters up to 182 days following insertion, avoiding the need for long term anticoagulation.
目的
肺栓塞(PE)是常见的死亡和发病原因。抗凝治疗可降低PE风险,但会增加出血风险。下腔静脉(IVC)滤器可预防PE,但长期深静脉血栓形成(DVT)风险增加。临时性IVC滤器可在高危情况下预防PE,后期可取出,避免长期抗凝。
方法
我们介绍了使用Recovery(巴德公司,亚利桑那州坦佩)和Tulip(库克公司,印第安纳州布卢明顿)可取出滤器的经验。
结果
计划为121例患者置入可取出滤器。平均年龄:58.8岁;男性72例。适应证包括:已确诊静脉血栓栓塞症(VTE)且有抗凝禁忌证;VTE高危且需进行出血风险高的手术;尽管进行了抗凝治疗,VTE仍有进展。113例患者顺利置入可取出滤器,无严重并发症。有2例确诊PE。随访期间共有27例患者死亡。1例死亡与滤器移位确诊相关。1例疑似恶性肿瘤患者突然不明原因死亡。58例患者平均在44天时尝试取出滤器,52例成功取出。30例取出的滤器中发现有血栓,但29例未影响取出。
结论
可取出IVC滤器在预防高危患者PE方面安全有效。我们已证明在滤器置入后长达182天取出滤器成功,避免了长期抗凝的需要。