Department of Anesthesiology, NO. 1 People's Hospital of Yibin, Yibin, Sichuan, China.
J Clin Monit Comput. 2010 Apr;24(2):149-53. doi: 10.1007/s10877-010-9227-3. Epub 2010 Mar 12.
Trachea is an alternative site for pulse oxygen saturation monitoring. The response time of the oximetry probe has been reported more rapid when placed in central than in peripheral. The purpose of this study is to compare the performance of the oximetry probes placed in trachea and peripheral site during rapid desaturation.
Endotracheal tubes with an oximetry sensor were intubated in ten anesthesia dogs. Both the oxygen saturation signals from trachea (S(t)O(2)) and tail (S(p)O(2)) were shown on the same monitoring screen. The mechanical ventilation was disconnected to produce a rapid desaturation when both S(t)O(2) and S(p)O(2) were 100%, and the mechanical ventilation was reconnected when S(p)O(2) decreased to 80%. The time of S(t)O(2) and S(p)O(2) dropped to 95, 90, 85, and 80% was recorded, respectively during the mechanical ventilation disconnection, and the arterial blood was sampled for arterial oxygen saturation (S(a)O(2)) measurement simultaneously. The levels of measurement agreement between two oximetry readings (S(p)O(2), S(t)O(2)) and S(a)O(2) were analyzed, respectively with the Bland and Altman method.
The mean response time of S(t)O(2) was significantly shorter than S(p)O(2) when both of them decreased from 100 to 80% (172.6+/-68.9 vs 220.7+/-72.3 s) during rapid desaturation. The 95% confidence interval for absolute difference between S(p)O(2) and S(a)O(2) was 4.12+/-6.47%, and between S(t)O(2) and S(a)O(2) was 3.33-3.46%.
Oxymetry placed in trachea provides a better monitoring for detecting rapid desaturation than in peripheral.
气管是脉搏血氧饱和度监测的替代部位。当血氧探头放置在中心位置时,其响应时间比放置在周围位置时更快。本研究的目的是比较在快速脱氧期间放置在气管和周围部位的血氧探头的性能。
将带有血氧传感器的气管内导管插入十只麻醉犬中。气管(S(t)O(2))和尾巴(S(p)O(2))的血氧饱和度信号都显示在同一监测屏幕上。当 S(t)O(2)和 S(p)O(2)均为 100%时,断开机械通气以产生快速脱氧,当 S(p)O(2)降至 80%时,重新连接机械通气。记录机械通气断开时 S(t)O(2)和 S(p)O(2)分别降至 95%、90%、85%和 80%的时间,同时采集动脉血进行动脉血氧饱和度(S(a)O(2))测量。分别采用 Bland 和 Altman 法分析两种血氧读数(S(p)O(2)、S(t)O(2))与 S(a)O(2)之间的测量一致性水平。
在快速脱氧期间,当 S(t)O(2)和 S(p)O(2)从 100%降至 80%时,S(t)O(2)的平均响应时间明显短于 S(p)O(2)(172.6+/-68.9 与 220.7+/-72.3 s)。S(p)O(2)和 S(a)O(2)之间的绝对差值的 95%置信区间为 4.12+/-6.47%,S(t)O(2)和 S(a)O(2)之间的差值为 3.33-3.46%。
与周围部位相比,气管内放置的血氧仪更能监测到快速脱氧。