Department of Radiology, Division of Interventional Neuroradiology, KEM Hospital, Mumbai, India.
Neurol India. 2010 Jan-Feb;58(1):62-8. doi: 10.4103/0028-3886.60400.
We aim to focus on the treatment of intracranial dural arteriovenous fistulas (DAVF) with emphasis on the evolution of endovascular management at our center over the last 13 years. We also aim to highlight the present treatment strategy, considering all the embolic agents available with us.
This is a retrospective study of 99 patients of DAVFs treated from December 1995 to March 2009.
Seven patients were found to have spontaneous thrombosis when taken up for treatment. The other 92 patients underwent endovascular treatment through transarterial or transvenous routes using polyvinyl alcohol particles, glue, detachable platinum coils or injection onyx as embolic agents. The treatment strategies have evolved over a period of time with changing philosophies and availability of different embolic agents.
Transverse- sigmoid and cavernous sinuses were the commonest sites of DAVFs. Intracranial hemorrhage was common presentation. Transarterial PVA embolization was performed in four patients, transarterial glue in 15, transvenous embolization in 33 and transarterial Onyx in 36. Direct puncture and packing of the sinuses was done in four patients. Cure was achieved in 80 out of 92 patients (cure rate of 87%). Patients who had Onyx embolization had cure rate of 92% (33 out of 36 patients). 14 complications were seen of which two were in the Onyx group.
Embolization of DAVFs has evolved over the last decade and has become the treatment of choice with high cure rates and improved safety. We propose the use of Onyx as the embolic agent of choice in the treatment of DAVFs.
我们旨在关注颅内硬脑膜动静脉瘘(DAVF)的治疗,重点介绍我们中心在过去 13 年中血管内治疗的演变。我们还旨在强调目前的治疗策略,考虑到我们所有可用的栓塞剂。
这是一项回顾性研究,共纳入了 99 例 DAVF 患者,治疗时间为 1995 年 12 月至 2009 年 3 月。
7 例患者在接受治疗时发现自发性血栓形成。其余 92 例患者通过经动脉或经静脉途径,使用聚乙烯醇颗粒、胶水、可解脱的铂金线圈或注射 ONYX 作为栓塞剂进行血管内治疗。随着时间的推移,治疗策略发生了变化,治疗理念和不同栓塞剂的应用也在不断变化。
横窦-乙状窦和海绵窦是 DAVF 最常见的部位。颅内出血是常见的表现。4 例患者行经动脉 PVA 栓塞,15 例患者行经动脉胶水栓塞,33 例患者行经静脉栓塞,36 例患者行经动脉 ONYX 栓塞。4 例患者行窦直接穿刺和填塞。92 例患者中的 80 例(治愈率为 87%)达到治愈。行 ONYX 栓塞的患者治愈率为 92%(33 例患者)。共发生 14 例并发症,其中 2 例发生在 ONYX 组。
DAVF 的栓塞治疗在过去十年中得到了发展,并已成为首选治疗方法,治愈率高,安全性提高。我们建议使用 ONYX 作为 DAVF 治疗的首选栓塞剂。