鞘内巴氯芬泵植入治疗僵人综合征 1 例。

Intrathecal baclofen pump implantation in a case of stiff person syndrome.

机构信息

Department of Neurology, Lourdes Heart Institute and Neuro Centre, Kochi, Kerala, India.

出版信息

Neurol India. 2010 Jan-Feb;58(1):115-7. doi: 10.4103/0028-3886.60420.

PMID:20228478

Abstract

Stiff person syndrome (SPS) is a rare disorder characterized by severe axial and/or limb rigidity, spasms and continuous motor unit activity on EMG. Symptomatically these patients are usually treated with GABAergic medications. We present a 45-year-old woman with SPS, who failed high dose of GABAergic medication. With intrathecal baclofen by intrathecal baclofen pump she had a significant improvement in her symptoms and quality of life.

摘要

僵人综合征（SPS）是一种罕见的疾病，其特征是严重的轴向和/或肢体僵硬、痉挛和肌电图上持续的运动单位活动。这些患者通常通过 GABA 能药物进行对症治疗。我们报告了一例 45 岁的 SPS 女性患者，她对高剂量的 GABA 能药物治疗无效。通过鞘内巴氯芬泵鞘内给予巴氯芬，她的症状和生活质量有了显著改善。