Weigl Wojciech, Szymusik Iwona, Borowska-Solonynko Aleksandra, Kosińska-Kaczyńska Katarzyna, Mayzner-Zawadzka Ewa, Bomba-Opoń Dorota, Matusiak Robert
I Klinika Anestezjologii i Intensywnej Terapii WUM, Warszawa.
Ginekol Pol. 2010 Jan;81(1):41-5.
The aim of the study was to analyze the influence of epidural analgesia (EA) on the course of labor.
The study group consisted of 191 women with EA ("walking anesthesia"). 209 women without EA were chosen for controls. All the patients delivered at the 1st Dept of Obstetrics and Gynecology Medical University of Warsaw, Poland. T-test and chi2 test were used for statistical analysis and p < 0.05 was considered statistically significant.
There were no significant differences between the groups regarding age, parity weight, average birth weight of newborns and the rate of preterm deliveries. The first and second stage of labor were significantly longer in EA group (p < 0.01). The velocity of dilatation was significantly slower in the study group until 3-5cm (0.87 vs. 1.34 cm/h). After EA was applied, the acceleration of dilatation was, however significantly greater than among controls (4.27 times vs. 3.2 times). The rate of CS was similar in both groups, however the indications for it differed significantly: fetal asphyxia 22% vs. 50% (p = 0.04), occiput posterior 22% vs. 4% (p = 0.009) in EA vs. controls, respectively. There were no differences between the groups regarding the general condition of the newborns.
The overall longer first stage of labor in patients from the study group can result from the characteristics of women more than from EA itself, as EA seems to accelerate the dilatation of the cervix. EA does not affect the incidence of operative delivery however it may change the indications to cesarean section. EA has no impact on the condition of the newborns.
本研究旨在分析硬膜外镇痛(EA)对产程的影响。
研究组由191例接受EA(“行走麻醉”)的女性组成。选取209例未接受EA的女性作为对照组。所有患者均在波兰华沙医科大学第一妇产科分娩。采用t检验和卡方检验进行统计分析,p<0.05被认为具有统计学意义。
两组在年龄、产次、体重、新生儿平均出生体重和早产率方面无显著差异。EA组第一产程和第二产程明显更长(p<0.01)。在3 - 5厘米之前,研究组的宫颈扩张速度明显较慢(0.87 vs. 1.34厘米/小时)。然而,应用EA后,扩张加速明显大于对照组(4.27倍 vs. 3.2倍)。两组剖宫产率相似,但剖宫产指征差异显著:EA组胎儿窘迫为22%,对照组为50%(p = 0.04);EA组枕后位为22%,对照组为4%(p = 0.009)。两组新生儿一般状况无差异。
研究组患者第一产程总体较长可能更多是由于女性自身特征而非EA本身,因为EA似乎能加速宫颈扩张。EA不影响手术分娩的发生率,但可能改变剖宫产指征。EA对新生儿状况无影响。