Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China Center for Clinical Epidemiology & Evidence-Based Medicine, Second Military Medical University, Shanghai, China.
Colorectal Dis. 2011 Jun;13(6):658-62. doi: 10.1111/j.1463-1318.2010.02251.x. Epub 2010 Mar 10.
The diagnostic accuracy of colonoscopic features in predicting colorectal cancer (CRC) malignancy was studied.
Consecutive patients who underwent first-time colonoscopy for lower gastrointestinal (GI) symptoms from 1998 to 2009 were identified. Gender, age, symptoms, endoscopic and pathologic findings were reviewed.
There were 10,603 patients. The overall prevalence of malignancy was 3.0% (313). Among these, only 58% (181/313) had features indicative of tumour formation. The overall sensitivity and specificity was 9.6% and 94.1%, respectively. The overall positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio were 2.66, 0.96 and 2.77, respectively.
A large proportion of Chinese patients with CRC presented without features indicative of tumour formation.
研究结肠镜下特征对结直肠癌（CRC）恶性肿瘤的诊断准确性。
本研究纳入了 1998 年至 2009 年期间因下胃肠道（GI）症状首次接受结肠镜检查的连续患者。回顾了患者的性别、年龄、症状、内镜和病理检查结果。
共纳入 10603 例患者。恶性肿瘤的总体患病率为 3.0%（313 例）。其中，只有 58%（181/313）例患者具有肿瘤形成的特征。总体敏感性和特异性分别为 9.6%和 94.1%。总体阳性似然比、阴性似然比和诊断比值比分别为 2.66、0.96 和 2.77。
中国 CRC 患者中有很大一部分患者没有肿瘤形成的特征。
