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髋部骨折后的隐性失血。

The hidden blood loss after hip fracture.

机构信息

Department of Orthopaedic Trauma, Royal Infirmary, Little France, Old Dalkeith Road, Edinburgh EH16 4SU, Scotland.

出版信息

Injury. 2011 Feb;42(2):133-5. doi: 10.1016/j.injury.2010.02.015. Epub 2010 Mar 16.

Abstract

INTRODUCTION

Despite advances in surgical and anaesthetic techniques the mortality after hip fracture has not significantly changed in the last 40 years. Pre-operative anaemia is a risk factor for peri-operative death. We speculate that a significant proportion of the blood loss related to hip fractures has occurred prior to surgery. Identifying patients at risk of pre-operative anaemia can facilitate appropriate medical optimisation. This study is unique in its attempt to quantify the blood loss associated with the initial hip injury.

METHODS

In a retrospective study all patients with both a diagnosis of hip fracture and an operative delay of >48 h were assessed. The information collected included: fracture classification, serial haemoglobins and patient co-morbidities. The exclusion criteria included a pre-injury diagnosis of anaemia, anti-coagulation and gastrointestinal bleeds.

RESULTS

Between 2007/2008 sixty-eight intracapsular and fifty extracapsular hip fracture patients had serial haemoglobins and operative delays of >48 h (mean 75 h, range 48-270 h). The mean lowest recorded haemoglobin prior to surgery for both extracapsular and intracapsular fractures were 95.0 g/L (+/-SEM 2.2) and 108.5 g/L (+/-SEM 2.2) respectively. This difference was statistically significant (Student's t-test p<0.05). The mean haemoglobin drop in the extracapsular and intracapsular fracture groups was 20.2 g/L (range 0-49 g/L) and 14.9 g/L (range 0-59 g/L) respectively.

CONCLUSIONS

Hip fracture patients have a large drop in haemoglobin that is associated with the initial trauma rather than the operation. This highlights the need for anaesthetic and orthopaedic staff to be vigilant to the risk of pre-operative anaemia in this cohort of frail patients even when the initial haemoglobin is apparently normal.

摘要

简介

尽管在外科和麻醉技术方面取得了进步,但在过去的 40 年中,髋部骨折后的死亡率并没有显著改变。术前贫血是围手术期死亡的一个危险因素。我们推测,与髋部骨折相关的大量失血发生在手术之前。识别术前贫血风险患者可以促进适当的医疗优化。这项研究的独特之处在于尝试量化与初始髋部损伤相关的失血量。

方法

在一项回顾性研究中,评估了所有既有髋部骨折诊断又有手术延迟>48 小时的患者。收集的信息包括:骨折分类、连续血红蛋白和患者合并症。排除标准包括术前诊断为贫血、抗凝和胃肠道出血。

结果

2007/2008 年间,68 例囊内和 50 例外囊髋部骨折患者的连续血红蛋白和手术延迟时间>48 小时(平均 75 小时,范围 48-270 小时)。外囊和囊内骨折患者术前记录的最低血红蛋白平均值分别为 95.0 g/L(+/-SEM 2.2)和 108.5 g/L(+/-SEM 2.2)。这一差异具有统计学意义(Student's t 检验,p<0.05)。外囊和囊内骨折组的血红蛋白下降平均值分别为 20.2 g/L(范围 0-49 g/L)和 14.9 g/L(范围 0-59 g/L)。

结论

髋部骨折患者的血红蛋白大量下降与初始创伤有关,而与手术无关。这凸显了麻醉和骨科工作人员即使在初始血红蛋白似乎正常的情况下,也需要警惕这一脆弱患者群体术前贫血的风险。

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