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[脊髓血管母细胞瘤的诊断与外科治疗]

[Diagnosis and surgical treatment of spinal hemangioblastoma].

作者信息

Isu T, Abe H, Iwasaki Y, Akino M, Koyanagi I, Hida K, Miyasaka K, Saito H

机构信息

Department of Neurosurgery, Hokkaido University School of Medicine.

出版信息

No Shinkei Geka. 1991 Feb;19(2):149-55.

PMID:2023671
Abstract

Spinal hemangioblastoma is a rare tumor. Its incidence varies from 1.6 to 2.1% of primary spinal cord tumors. In this report, the authors described MRI (magnetic resonance imaging) of spinal hemangioblastoma and its surgical results. [MATERIALS AND METHODS] This series included 10 spinal hemangioblastomas studied with CT or MRI. There were 8 men and 2 women. The age ranged from 21 to 68 years, with a mean age of 45 years. 6 patients were preoperatively and postoperatively studied with a resistive 0.15 T system (Toshiba MRT 15A) or a superconductive 1.5 T system (GE Signa or Siemens Magnetom). The lesions were single in 8 out of 10 patients and multiple in 2. 10 spinal hemangioblastomas were located in intramedullary space and 2 in both intramedullary and extramedullary space. 8 out of 10 patients (80%) were associated with cyst. [RESULTS] (1) MRI In T1-weighted MR images after administration of Gd-DTPA, the solid component of the tumor enhanced brilliantly. The enhanced lesions contained serpiginous areas of signal void, reflecting vascular structures in 5 out of 6 cases. The intrinsic spinal cord signal was heterogenous with low intensity areas representing the associated cyst. The cyst appeared either isointensive to cerebrospinal fluid (CSF) or hyperintense relative to CSF and slightly hypointense relative to the spinal cord. The precise delineation of the tumor was impossible without enhancement. Noncontrast T1-weighted MR images displayed diffuse widening of the spinal cord. On T2-weighted MR images, all regions of the spinal cord enlargement increased in signal. (2) Postoperative results All 10 cases of spinal hemangioblastomas were totally removed with good postoperative results and the associated cysts were drained. The postoperative MRI showed the disappearance of the tumor and significant reduction in the size of the cyst. [CONCLUSION] (1) Gd-DTPA enhanced MRI was useful in defining and outlining the solid component of spinal hemangioblastoma. (2) The complete removal of the tumor with only drainage of the cyst was possible with good postoperative results.

摘要

脊髓血管母细胞瘤是一种罕见的肿瘤。其发病率占原发性脊髓肿瘤的1.6%至2.1%。在本报告中,作者描述了脊髓血管母细胞瘤的MRI(磁共振成像)表现及其手术结果。[材料与方法]本系列研究包括10例接受CT或MRI检查的脊髓血管母细胞瘤患者。其中男性8例,女性2例。年龄范围为21至68岁,平均年龄45岁。6例患者在术前和术后使用0.15T电阻式系统(东芝MRT 15A)或1.5T超导系统(GE Signa或西门子Magnetom)进行检查。10例患者中8例病变为单发,2例为多发。10例脊髓血管母细胞瘤位于髓内,2例位于髓内和髓外。10例患者中有8例(80%)伴有囊肿。[结果](1)MRI 在静脉注射钆喷酸葡胺后的T1加权磁共振图像上,肿瘤的实性部分明显强化。强化病变中有蜿蜒的无信号区,6例中有5例显示为血管结构。脊髓本身信号不均匀,低信号区代表相关囊肿。囊肿在T1加权像上信号强度与脑脊液(CSF)相同或相对于CSF呈高信号,相对于脊髓略呈低信号。未强化时无法精确勾勒肿瘤轮廓。平扫T1加权磁共振图像显示脊髓弥漫性增宽。在T2加权磁共振图像上,脊髓增粗的所有区域信号均增高。(2)术后结果 10例脊髓血管母细胞瘤均完全切除,术后效果良好,相关囊肿均已引流。术后MRI显示肿瘤消失,囊肿大小明显缩小。[结论](1)钆喷酸葡胺增强MRI有助于明确和勾勒脊髓血管母细胞瘤的实性部分。(2)仅通过囊肿引流即可完全切除肿瘤,术后效果良好。

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