Imperial Tobacco Canada Ltd., 3711 St-Antoine Street West, Montreal, Quebec, Canada.
Regul Toxicol Pharmacol. 2011 Dec 1;61(3 Suppl):S51-9. doi: 10.1016/j.yrtph.2010.03.004. Epub 2010 Mar 18.
In 2005, Human-Smoked (HS) tar and nicotine yields from commercial Canadian cigarettes were determined using a part filter analysis method to obtain estimates representative of human smoking behavior. In 2006, new cigarette designs were introduced to ensure compliance with the Canadian Low Ignition Propensity (LIP) regulations. It was not known how the changes in product design would affect HS yields. To assess the impact of the cigarette design modifications on HS yields, a further group of Canadian smokers was recruited for smoking the modified version of 10 products previously assessed. No differences in estimated HS tar yields were found between products following product modification. The HS nicotine yield was different for one product. In general, HS yields were higher than ISO machine yields while Canadian intense machine yields were more representative of the maximum HS yields. The same product ranking order was obtained for HS yields and the two machine yields but differences between the mean HS yields and ISO yields were smaller as the product ISO yields increased. Higher HS yields were measured when products were smoked by male smokers. The methodology used in this study showed the wide range of HS yields obtained by smokers as well as a good degree of stability in average HS yields just before and after the introduction of LIP regulations.
2005 年,使用部分滤嘴分析方法测定了加拿大商业香烟中的人吸烟焦油和尼古丁产率,以获得代表人体吸烟行为的估计值。2006 年,推出了新的香烟设计,以确保符合加拿大低点火倾向(LIP)法规。不知道产品设计的变化将如何影响人吸烟焦油量。为了评估香烟设计修改对人吸烟焦油量的影响,招募了另一组加拿大吸烟者,让他们吸以前评估过的 10 种产品的改良版。产品修改后,估计的人吸烟焦油产率没有差异。一种产品的人吸烟尼古丁产率不同。一般来说,人吸烟焦油量高于 ISO 机器焦油量,而加拿大浓味机器焦油量更能代表最大人吸烟焦油量。人吸烟焦油量和两种机器焦油量的产品排名顺序相同,但随着产品 ISO 焦油量的增加,人吸烟焦油量和 ISO 焦油量的平均值之间的差异变小。男性吸烟者吸烟时,人吸烟焦油量较高。本研究中使用的方法表明,吸烟者的人吸烟焦油量范围很广,并且在 LIP 法规出台前后,平均人吸烟焦油量的稳定性较好。