Awasthy Neeraj, Marwah Ashutosh, Sharma Rajesh, Dalvi Bharat
Department of Pediatric Cardiology, Escorts Heart Institute and Reseach Center (EHIRC), Okhla road, New Delhi 110025, India.
Eur J Echocardiogr. 2010 Sep;11(8):E31. doi: 10.1093/ejechocard/jeq039. Epub 2010 Mar 22.
Anomalous left coronary artery from the pulmonary trunk (ALCAPA) presents in early infancy with a clinical picture of congestive heart failure with left ventricular (LV) dysfunction and mitral insufficiency. These manifestations of myocardial ischaemia may be masked in the presence of an associated patent ductus arteriosus (PDA) or ventricular septal defect (VSD) which prevents the fall of pulmonary artery pressures and allows perfusion of the anomalous coronary artery. We present a case of a patient with large PDA-associated ALCAPA and preserved LV function. The importance of such a finding lies in the fact that VSD closure or PDA ligation in such cases would unmask the ALCAPA.
起源于肺动脉干的异常左冠状动脉(ALCAPA)在婴儿早期出现,临床表现为伴有左心室(LV)功能障碍和二尖瓣关闭不全的充血性心力衰竭。在存在相关动脉导管未闭(PDA)或室间隔缺损(VSD)的情况下,心肌缺血的这些表现可能会被掩盖,因为这可防止肺动脉压力下降并使异常冠状动脉得以灌注。我们报告一例患有大型PDA相关ALCAPA且LV功能保留的患者。这一发现的重要性在于,在此类病例中进行VSD闭合或PDA结扎会使ALCAPA暴露出来。