Qian G X
Southwest Hospital, third Military Medical College, Chongqing.
Zhonghua Wai Ke Za Zhi. 1991 Jan;29(1):59-62, 78.
Eighteen patients with acute pancreatitis(AP) were studied prospectively with a clinical analysis of 34 patients with ARDS caused by AHP. Ten of the 18 AP patients had lung damage demonstrated by PaO2 and P (A-a) O2, in which the elevation of the blood and alveolar levels of FFA and PLA also contributed to the pathogenesis of lung damage and ARDS. The 34 ARDS patients could be divided into 3 groups according to the speed with which ARDS developed, i.e. rapid, postoperatively rapid, and delayed occurring. It was also found that the mortality rate of ARDS was closely related to the number of organs involved in AHP. We suggested 8 risk factors of ARDS in AHP cases and discussed the etiology of ARDS, its early diagnosis, prophylaxis, and management.
对18例急性胰腺炎(AP)患者进行了前瞻性研究,并对34例由急性出血性胰腺炎(AHP)导致的急性呼吸窘迫综合征(ARDS)患者进行了临床分析。18例AP患者中有10例经动脉血氧分压(PaO2)和肺泡-动脉血氧分压差[P(A-a)O2]证实存在肺损伤,其中血液和肺泡中游离脂肪酸(FFA)及磷脂酶A(PLA)水平升高也促成了肺损伤和ARDS的发病机制。34例ARDS患者可根据ARDS发生的速度分为3组,即快速发生组、术后快速发生组和延迟发生组。还发现ARDS的死亡率与AHP累及的器官数量密切相关。我们提出了AHP病例中ARDS的8个危险因素,并讨论了ARDS的病因、早期诊断、预防及治疗。