Labar D, Petty G, Emerson R, Pedley T, Mohr J P
Neurological Institute of New York, Columbia Presbyterian Medical Center, NY 10032.
J Neurol Sci. 1991 Feb;101(2):221-6. doi: 10.1016/0022-510x(91)90049-d.
We recorded median nerve somatosensory evoked potentials (SSEPs) in 42 patients with small subcortical strokes associated with lacunar syndromes. Seventeen patients had abnormal SSEPs. The P22 component was most often affected; changes in N20 and N18 were less common. Four patients with pure motor strokes (PMS) had abnormal SSEPs. Abnormalities of P22 correlated best with motor findings; those of N20 with sensory signs and symptoms. Similar SSEP abnormalities were produced by lesions in various locations. P22 and N20 abnormalities occurred independently and together. We conclude: (1) abnormal SSEPs are common in patients with small subcortical strokes associated with lacunar syndromes, including pure motor stroke; (2) P22 and N20 have separate cortical generators; and (3) P22 may be generated within sensory pathways which are adjacent to or influenced by motor pathways.
我们记录了42例伴有腔隙综合征的小皮质下卒中患者的正中神经体感诱发电位（SSEP）。17例患者的SSEP异常。P22成分最常受影响；N20和N18的变化较少见。4例纯运动性卒中（PMS）患者的SSEP异常。P22异常与运动表现相关性最好；N20异常与感觉体征和症状相关性最好。不同部位的病变均可产生类似的SSEP异常。P22和N20异常可单独出现，也可同时出现。我们得出以下结论：（1）伴有腔隙综合征的小皮质下卒中患者，包括纯运动性卒中患者，SSEP异常很常见；（2）P22和N20有独立的皮质发生器；（3）P22可能在与运动通路相邻或受其影响的感觉通路中产生。
