Division of Biostatistics, Centre for Epidemiology and Biostatistics, University of Leeds, Leeds, UK.
J Hum Hypertens. 2011 Feb;25(2):88-97. doi: 10.1038/jhh.2010.33. Epub 2010 Mar 25.
In the last decades, the prevalence of obesity has increased in the Taiwanese population. This has the potential to impact on the risks of cardiovascular diseases and diabetes. This study investigated trends in the changes in several indices of obesity in the last decade, and the relationship between blood pressure (BP) and these obesity indices available in Mei-Jaw Corporation health-screening data from 1996/1998 to 2006. Three cross-sectional surveys among healthy individuals ages 20-59 years, in which 14,362 subjects examined in year 1996, 17,368 in 1998, and 28,524 in 2006, were included in the analysis. Body weight and height data were available from 1996, whereas %body fat, waist circumference and waist-hip ratio (Whratio) were only available from 1998 onwards. We found that the association between systolic BP and body weight, body mass index, %body fat, Whratio and waist became stronger for both men and women in 2006 than 1996 after adjustment for age, education level, alcohol intake, smoking and betel nut chewing. In contrast, non-obese people seemed to have lower diastolic BP in 2006 than in 1996. This trend is consistent irrespective of the index of obesity used. Among healthy individuals, the average values for the obesity indices increased in men but remained similar in women. However, in both men and women, the relationship between obesity and BP has changed. Further research is required to investigate the impact of these intriguing changes in the associations on the risk of cardiovascular diseases in the Taiwanese population.
在过去的几十年中,台湾人口中肥胖的流行率有所增加。这有可能影响到心血管疾病和糖尿病的风险。本研究调查了过去十年中几种肥胖指数变化的趋势,以及 1996/1998 年至 2006 年美兆体检数据中血压(BP)与这些肥胖指数之间的关系。对年龄在 20-59 岁之间的健康个体进行了三项横断面调查,其中 1996 年检查了 14362 例,1998 年检查了 17368 例,2006 年检查了 28524 例。分析中包括了这些数据。1996 年可获得体重和身高数据,而从 1998 年开始仅可获得体脂肪百分比、腰围和腰臀比(Whratio)数据。我们发现,调整年龄、教育程度、饮酒、吸烟和嚼槟榔后,2006 年男性和女性的收缩压与体重、体重指数、体脂肪百分比、Whratio 和腰围之间的关联比 1996 年更强。相比之下,2006 年非肥胖人群的舒张压似乎比 1996 年更低。这种趋势与使用的肥胖指数无关。在健康个体中,男性的肥胖指数平均值增加,但女性的肥胖指数平均值保持不变。然而,无论肥胖指数如何,肥胖与 BP 的关系都发生了变化。需要进一步的研究来探讨这些关联变化对台湾人群心血管疾病风险的影响。