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[急性呼吸窘迫综合征:循环因素及其评估]

[ARDS: circulatory factors and their evaluation].

作者信息

Imamura T

机构信息

The Second Department of Internal Medicine, Nagasaki University School of Medicine.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Feb;29(2):145-52.

PMID:2033888
Abstract

ARDS occurs in patients with no underlying pulmonary diseases, induced by stresses, such as lung injury, acute pancreatitis or infections. It is an acute respiratory disorder which manifests as acute dyspnea, hypoxemia and lowered pulmonary compliance. Greene et al, used balloon pulmonary angiogram (BOPA) as diagnostic tool to morphologically observe the pulmonary disorder. To study the dynamic pulmonary circulation and morphology of the peripheral pulmonary artery of ARDS, we performed this method for acute cardiac failure and ARDS patients. Pulmonary hemodynamic changes in ARDS revealed mild pulmonary hypertension and increased PVR, while C.I. and PCWP remained within a normal range. The findings of BOPA in ARDS showed that the frequency of PAFD correlated with the the presence of an elevated PVR and DIC, and pulmonary vasoconstriction was detected by measurement of PA diameter (B/A2).

摘要

急性呼吸窘迫综合征(ARDS)发生于无潜在肺部疾病的患者,由诸如肺损伤、急性胰腺炎或感染等应激因素诱发。它是一种急性呼吸障碍,表现为急性呼吸困难、低氧血症和肺顺应性降低。格林等人使用球囊肺血管造影术(BOPA)作为诊断工具,从形态学上观察肺部疾病。为研究ARDS患者的动态肺循环及外周肺动脉形态,我们对急性心力衰竭和ARDS患者实施了该方法。ARDS患者的肺血流动力学变化显示轻度肺动脉高压和肺血管阻力(PVR)增加,而心脏指数(C.I.)和肺毛细血管楔压(PCWP)仍在正常范围内。ARDS患者的BOPA检查结果表明,外周肺动脉分支减少(PAFD)的频率与PVR升高和弥散性血管内凝血(DIC)的存在相关,并且通过测量肺动脉直径(B/A2)检测到肺血管收缩。

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