Neuropsychiatric Branch, Department of Internal Medicine, School of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Braz J Psychiatry. 2010 Mar;32(1):62-5. doi: 10.1590/s1516-44462010000100012.
To investigate the frequency of bipolar disorder, dopamine dysregulation syndrome and punding in Parkinson's disease patients from a Brazilian movement disorders clinic.
One hundred patients underwent a comprehensive psychiatric examination composed of MINI-plus and specific questionnaires to investigate dopamine dysregulation syndrome and punding.
We identified, respectively, one and five Parkinson's disease patients with bipolar disorder type I and type II. All manic/hypomanic episodes occurred before Parkinson's disease onset. No patient was identified with dopamine dysregulation syndrome or punding.
The frequency of manic/hypomanic episodes seems to decrease with Parkinson's disease onset, and local environmental factors (e.g. drug availability) may be responsible for the low frequency of dopamine dysregulation syndrome and punding in Brazilian Parkinson's disease patients.
从巴西运动障碍诊所的帕金森病患者中调查双相障碍、多巴胺失调综合征和冲动控制障碍的频率。
100 名患者接受了综合精神病学检查，包括 MINI-plus 和专门的问卷，以调查多巴胺失调综合征和冲动控制障碍。
我们分别发现了 1 例和 5 例帕金森病患者患有 I 型和 II 型双相障碍。所有躁狂/轻躁狂发作均发生在帕金森病发病之前。没有患者被诊断为多巴胺失调综合征或冲动控制障碍。
躁狂/轻躁狂发作的频率似乎随着帕金森病的发病而降低，而局部环境因素（例如药物可用性）可能是巴西帕金森病患者中多巴胺失调综合征和冲动控制障碍发生率较低的原因。
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