Cohen S R, Kalinowski J, LaRossa D, Randall P
Craniofacial Anomalies Program, C. S. Mott Children's Hospital, Ann Arbor, Mich.
Plast Reconstr Surg. 1991 Jun;87(6):1041-7.
A retrospective, multivariate statistical analysis of 129 consecutive nonsyndromic patients undergoing cleft palate repair was performed to document the incidence of postoperative fistulas, to determine their cause, and to review methods of surgical management. Nasal-alveolar fistulas and/or anterior palatal fistulas that were intentionally not repaired were excluded from study. Cleft palate fistulas (CPFs) occurred in 30 of 129 patients (23 percent), although nearly a half were 1 to 2 mm in size. Extent of clefting, as estimated by the Veau classification, was significantly more severe in those patients who developed cleft palate fistula. Type of palate closure also influenced the frequency of cleft palate fistula. Forty-three percent of patients undergoing Wardill-type closures developed cleft palate fistula versus 10, 22, and 0 percent for Furlow, von Langenbeck, and Dorrance style closures, respectively. The fistula rate was similar in patients with (30 percent) and without (25 percent) intravelar veloplasty. Age at palate closure did not significantly affect the rate of fistulization; however, the surgeon performing the initial closure did not have an effect. Thirty-seven percent of patients developed recurrent cleft palate fistulas following initial fistula repair. Recurrence of cleft palate fistulas was not influenced by severity of cleft or type of original palate repair. Following end-stage management, a second cleft palate fistula recurrence occurred in 25 percent of patients. Continued open discussion of results of cleft palate repair is recommended.
对129例连续接受腭裂修复术的非综合征患者进行了回顾性多变量统计分析,以记录术后瘘管的发生率,确定其原因,并回顾手术治疗方法。故意未修复的鼻牙槽瘘和/或前腭裂瘘被排除在研究之外。129例患者中有30例(23%)发生了腭裂瘘(CPF),尽管近一半的瘘管大小为1至2毫米。根据Veau分类法估计,发生腭裂瘘的患者腭裂程度明显更严重。腭裂修复方式也影响腭裂瘘的发生率。接受Wardill式修复的患者中有43%发生了腭裂瘘,而Furlow、von Langenbeck和Dorrance式修复的发生率分别为10%、22%和0%。行或未行腭内肌成形术的患者瘘管发生率相似(分别为30%和25%)。腭裂修复时的年龄对瘘管形成率无显著影响;然而,进行初次修复的外科医生对此并无影响。37%的患者在初次瘘管修复后发生复发性腭裂瘘。腭裂瘘的复发不受腭裂严重程度或初次腭裂修复方式的影响。在最终治疗后,25%的患者发生了第二次腭裂瘘复发。建议对腭裂修复结果进行持续公开的讨论。