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新型主动脉弓病变血管腔内治疗中简化联合开放手术的主动脉弓血管套叠吻合新技术

Novel sutureless telescoping anastomosis revascularization technique of supra-aortic vessels to simplify combined open endovascular procedures in the treatment of aortic arch pathologies.

机构信息

Clinic for Cardiovascular Surgery, University Hospital of Zurich, Zurich, Switzerland.

出版信息

J Vasc Surg. 2010 Apr;51(4):836-41. doi: 10.1016/j.jvs.2009.09.054.

Abstract

BACKGROUND

We report our clinical experience with the use of a sutureless telescoping anastomosis, initially described as the VORTEC (Viabahn Open Rebranching TEChnique) revascularization technique, for debranching of supra-aortic vessels.

METHODS

Between May 2005 and December 2008, 20 patients (15 men) with an aortic arch lesion underwent trans-sternal debranching with sutureless telescoping anastomosis performed with a Viabahn (diameter, 5-8 mm; length, 5-15 cm) or Hemobahn (diameter, 9-13 mm; length, 10-15 cm), followed by endovascular aneurysm repair. Initially, the Viabahn/Hemobahn was sutured to a feeding graft after deployment. Since 2008, the Viabahn/Hemobahn has been deployed within an interposition graft, rendering unnecessary the anastomosis. The underlying aortic pathology was (1) isolated aortic arch aneurysm in 10, (2) aortic arch aneurysm extending to the ascending or descending aorta in 6, (3) floating thrombus within the aortic arch in 1, (4) acute aortic arch dissection in 1, and (5) Crawford II thoracoabdominal aortic aneurysm extending into the aortic arch in 2. Postprocedural duplex ultrasound imaging showed normal flow profiles in all patients. Follow-up included computed tomography angiography at 1, 3, and 6 months postoperatively, and then annually.

RESULTS

Overall, 56 supra-aortic vessels in the 20 patients were debranched by sutureless telescoping anastomosis, including the carotid artery in 18, subclavian artery in 13, and left vertebral artery in 1. Technical success was 100%. The mean ischemia time was 3 minutes (range, 1-9 minutes) for the debranching procedure vs 6 minutes (range, 5-16 minutes) for a conventional suture anastomosis. The 30-day mortality rate was 15% (3 if 20); 28.5% (2 of 7) in urgent cases and 7.6% (1 of 12) in elective patients. Three patients (15%) had neurologic deficits after debranching in the conventionally-sutured anastomosis territories. No early (<30 days) occlusion occurred. During a mean follow-up of 14 +/- 9 months (range, 1-39 months), one patient with Takayasu disease showed asymptomatic occlusion of a Viabahn implanted into the left common carotid artery. Stenosis in the aortic anastomosis of the bypass graft in another patient was successfully treated by angioplasty and stent placement through the right brachial artery.

CONCLUSIONS

Sutureless telescoping anastomosis with a Viabahn or a Hemobahn in supra-aortic debranching seems to be a safe and reliable alternative to sutured anastomosis. It enables safe and fast-track revascularizations, especially in anatomically challenging situations, and requires a very short ischemia time. Questions about long-term results and the technique reproducibility must be addressed.

摘要

背景

我们报告了使用无缝线套管吻合术(最初称为 VORTEC(Viabahn 开放再分支技术)血管重建技术)进行主动脉弓分支血管去分支的临床经验。

方法

2005 年 5 月至 2008 年 12 月,20 例(男 15 例)主动脉弓病变患者接受经胸骨分支去分支术,采用 Viabahn(直径 5-8mm;长度 5-15cm)或 Hemobahn(直径 9-13mm;长度 10-15cm)进行无缝线套管吻合术,随后行血管内动脉瘤修复术。最初,Viabahn/Hemobahn 在部署后缝合到供体移植物上。自 2008 年以来,Viabahn/Hemobahn 已在中间移植物内展开,从而无需进行吻合术。主动脉的潜在病变为:孤立的主动脉弓动脉瘤 10 例,主动脉弓动脉瘤延伸至升主动脉或降主动脉 6 例,主动脉弓内漂浮血栓 1 例,急性主动脉弓夹层 1 例,Crawford II 胸腹主动脉瘤延伸至主动脉弓 2 例。术后经颅超声检查显示所有患者的血流均正常。随访包括术后 1、3 和 6 个月行 CT 血管造影检查,然后每年一次。

结果

20 例患者中,56 个主动脉弓分支血管通过无缝线套管吻合术进行了去分支,其中颈动脉 18 个,锁骨下动脉 13 个,左椎动脉 1 个。技术成功率为 100%。分支手术的平均缺血时间为 3 分钟(1-9 分钟),而传统缝线吻合术的平均缺血时间为 6 分钟(5-16 分钟)。30 天死亡率为 15%(20 例中有 3 例);紧急情况下为 28.5%(7 例中有 2 例),择期情况下为 7.6%(12 例中有 1 例)。3 例(15%)在常规缝合吻合术区域分支后出现神经功能缺损。无早期(<30 天)闭塞发生。在平均 14+/-9 个月(1-39 个月)的随访中,1 例 Takayasu 病患者的左颈总动脉植入的 Viabahn 出现无症状闭塞。另一名患者旁路移植血管主动脉吻合口狭窄,通过右肱动脉成功行血管成形术和支架置入治疗。

结论

主动脉弓分支血管去分支术采用 Viabahn 或 Hemobahn 的无缝线套管吻合术似乎是一种安全可靠的替代缝线吻合术的方法。它能够安全快速地进行血管重建,特别是在解剖学上具有挑战性的情况下,且需要非常短的缺血时间。关于长期结果和技术可重复性的问题仍需解决。

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