多囊卵巢综合征的晚期妊娠并发症
Late pregnancy complications in polycystic ovarian syndrome.
作者信息
Katsikis I, Kita M, Karkanaki A, Prapas N, Panidis D
机构信息
Division of Endocrinology and Human Reproduction, 2nd Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
出版信息
Hippokratia. 2006 Jul;10(3):105-11.
Gestational diabetes mellitus and new-onset hypertension, which includes gestational hypertension and pre-eclampsia, are common complications of pregnancy. Many features of the insulin resistance syndrome have been associated with these conditions. These include glucose intolerance, hyperinsulinemia, hypertension, obesity, and lipid abnormalities. Other accompanying abnormalities may include elevated serum levels of leptin, TNFalpha, plasminogen activator inhibitor-1 and testosterone. The establishment of these features before the onset of gestational diabetes mellitus and hypertension in pregnancy suggests that insulin resistance or associated abnormalities may play a role in these disorders. These observations suggest that therapeutic interventions to reduce insulin resistance may lower the risk of both gestational diabetes mellitus and hypertension in pregnancy.
妊娠期糖尿病和新发高血压（包括妊娠高血压和先兆子痫）是常见的妊娠并发症。胰岛素抵抗综合征的许多特征都与这些病症有关。这些特征包括葡萄糖不耐受、高胰岛素血症、高血压、肥胖和脂质异常。其他伴随的异常情况可能包括血清瘦素、肿瘤坏死因子α、纤溶酶原激活物抑制剂-1和睾酮水平升高。在妊娠期糖尿病和妊娠高血压发病之前出现这些特征表明，胰岛素抵抗或相关异常可能在这些疾病中起作用。这些观察结果表明，降低胰岛素抵抗的治疗干预措施可能会降低妊娠期糖尿病和妊娠高血压的风险。
Zotero 插件