Department of Orthopedic Surgery, Nagoya City Rehabilitation Center, 1-2 Mikanyama Yatomi-cho, Mizuho-ku, Nagoya, Japan.
Spine (Phila Pa 1976). 2010 Apr 15;35(8):E290-4. doi: 10.1097/BRS.0b013e3181c84700.
A retrospective comparison of magnetic resonance imaging (MRI) and quantitative electromyography (EMG) findings in patients with compressive cervical myelopathy (CCM).
To investigate which parameters of the EMG motor unit potentials (MUPs) as determined by automatic analysis of 4 muscles in the upper limb are correlated with spinal cord compression observed on MRI in CCM patients and to determine whether electrical and radiologic levels are correlated.
Increased mean duration of MUPs has been reported to be a sensitive indicator of disorders of the spinal motor neurons that are accompanied by axonal degeneration and regeneration.
MRI findings at each cervical disc level from C3/C4 to C6/C7 and MUPs recorded from 4 muscles (deltoid, biceps brachii, triceps brachii, and abductor digiti minimi) were examined to determine whether there is a statistical correlation between spinal cord compression and abnormal parameters of the MUPs for any combination of disc level and muscle.
Significant correlations between increased mean duration of MUPs and radiologic level of cord compression were observed for deltoid and cord compression at C3/C4 (P < 0.01), biceps brachii and cord compression at C3/C4 (P < 0.001) and C4/C5 (P < 0.01), triceps brachii and cord compression at C5/C6 (P < 0.05), and abductor digiti minimi and cord compression at C6/C7 (P < 0.001). Other parameters of MUPs including amplitude, polyphasia and denervation potentials did not show significant correlation with compressive spinal cord lesions on MRI.
Quantitative analysis of mean duration of MUPs provides a reliable indicator of physiologic disorder of spinal motor neurons in CCM and may contribute to establishing the site of motor neuron compromise in cases with multilevel spinal canal stenosis.
对压迫性颈髓病（CCM）患者的磁共振成像（MRI）和定量肌电图（EMG）检查结果进行回顾性比较。
研究通过自动分析上肢 4 块肌肉的 EMG 运动单位电位（MUP）的哪些参数与 CCM 患者 MRI 观察到的脊髓压迫有关，并确定电生理水平是否相关。
已有报道称，MUP 的平均持续时间增加是脊髓运动神经元功能障碍的敏感指标，这种功能障碍伴有轴突变性和再生。
检查 C3/C4 至 C6/C7 每个颈椎间盘水平的 MRI 发现和 4 块肌肉（三角肌、肱二头肌、肱三头肌和小指展肌）记录的 MUP，以确定在任何椎间盘水平和肌肉组合中，脊髓压迫与 MUP 的异常参数之间是否存在统计学相关性。
观察到三角肌和 C3/C4 节段的脊髓压迫（P < 0.01）、肱二头肌和 C3/C4 节段的脊髓压迫（P < 0.001）和 C4/C5 节段的脊髓压迫（P < 0.01）、肱三头肌和 C5/C6 节段的脊髓压迫（P < 0.05）以及小指展肌和 C6/C7 节段的脊髓压迫（P < 0.001）之间，MUP 的平均持续时间增加与放射学水平的脊髓压迫之间存在显著相关性。MUP 的其他参数，包括幅度、多相性和失神经电位，与 MRI 上的压迫性脊髓病变无显著相关性。
MUP 平均持续时间的定量分析为 CCM 中脊髓运动神经元的生理功能障碍提供了可靠的指标，可能有助于确定多节段椎管狭窄症中运动神经元受损的部位。
