[比较呼气末负压技术与传统测试在检测慢性阻塞性肺疾病患者呼气气流受限中的作用。]

[To compare negative expiratory pressure technique with conventional tests in detecting expiratory flow limitation in chronic obstructive pulmonary diseases patients.].

作者信息

Chen Rui, Chen Rong-Chang, Liu Jie, Cen Yan-Yi, Chen Lian

机构信息

State Key Lab of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China. Email:

出版信息

Zhonghua Nei Ke Za Zhi. 2010 Feb;49(2):122-4.

PMID:20356508

Abstract

OBJECTIVE

To compare negative expiratory pressure (NEP) technique with conventional test in detecting expiratory flow limitation (EFL) in chronic obstructive pulmonary diseases (COPD) patients.

METHODS

EFL was measured with NEP technique and conventional method respectively in 72 COPD patients;EFL was measured with NEP technique in 20 COPD patients who failed to perform conventional test.

RESULTS

EFL was detected in 54 of the 72 COPD patients. NEP test was successfully performed on the 20 patients, and 19 of them were found with EFL. The level of forced expired volume in one second percentage (FEV(1)%) of the patients with 2-score group (46.92 +/- 12.74)% and 3-score group (33.35 +/- 8.96)% were significantly lower than that of the 1-score group (63.60 +/- 16.65)%. Area under curve of NEP technique and conventional test in ROC is 0.903 and 0.761 respectively.

CONCLUSIONS

As compared with conventional test, EFL detected with NEP technique is more reliable in evaluating dyspnea of COPD patients. It is simple and doesn't require any cooperation of the patients. NEP technique can be applied in COPD patients who fail to receive conventional test.

摘要

目的

比较呼气负压（NEP）技术与传统检测方法在慢性阻塞性肺疾病（COPD）患者中检测呼气流量受限（EFL）的效果。

方法

分别采用NEP技术和传统方法对72例COPD患者进行EFL检测；对20例无法进行传统检测的COPD患者采用NEP技术进行EFL检测。

结果

72例COPD患者中54例检测到EFL。20例患者成功进行了NEP检测，其中19例检测到EFL。2分评分组患者的一秒用力呼气容积百分比（FEV(1)%）水平为（46.92±12.74）%，3分评分组为（33.35±8.96）%，均显著低于1分评分组的（63.60±16.65）%。NEP技术和传统检测方法在ROC曲线下面积分别为0.903和0.761。