Wu Fei, Liu Jixiang, Zhang Zhijian, Bi Wei, Shen Na
Graduate School, Tianjin Medical University, Tianjin, 300070, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 Nov;23(22):1023-6.
To analyze normal pure tone hearing thresholds patients with aural fullness using evoked otoacoustic emission in order to detect the early cochlear impairment.
Forty-three normal pure tone hearing thresholds patients (72 ears, aural fullness group) with aural fullness were served as subjects and 30 normal volunteers (60 ears, control group) as controls. Transiently evoked otoacoustic emission (TEQAF) and distortion product evoked otoacoustic emission (DPOAE) were tested with Capella otoacoustic emission machine. The DPOAE detection rate and amplitudes at all frequencies,the passing rate and wave signal noise ratio (SNR) ,wave reproducibility, band SNR and band reproducibility of TEOAE were recorded and analyzed.
(1) Only on the frequency points of 0.50 kHz and 0.75 kHz, the detection rate of DPOAE in aural fullness group was lower than that in control group (P < 0.05). There was no significant difference in the rate among other frequency points (P > 0.05). (2) The passing rate of TEOAE was 100w in control group and 90. in aural fullness group. There were statistical differences between two groups (chi2 = 6.16, P < 0.05). (3) Compared with the control group, the DPOAE amplitudes at all frequencies, the wave signal noise ratio (SNR), wave reproducibility, band SNR and band reproducibility of TEOAE in patients with aural fullness were significantly decreased. There were statistical differences (P < 0.05 or P < 0.01).
Some patients of normal hearing thresholds with aural fullness have had early harm of Outer hair cell in cochlear. TEOAE and DPOAE may he used to detect these lesions early before the hearing impairment occurred.
采用诱发耳声发射分析纯音听阈正常的耳闷患者,以检测早期耳蜗损伤。
选取43例纯音听阈正常的耳闷患者(72耳,耳闷组)作为研究对象,30例正常志愿者(60耳,对照组)作为对照。使用Capella耳声发射仪检测瞬态诱发耳声发射(TEOAE)和畸变产物耳声发射(DPOAE)。记录并分析DPOAE在各频率的检出率及幅值、TEOAE的通过率及波信号噪声比(SNR)、波重复性、频段SNR及频段重复性。
(1)仅在0.50kHz和0.75kHz频率点,耳闷组DPOAE的检出率低于对照组(P<0.05),其他频率点两组间差异无统计学意义(P>0.05)。(2)对照组TEOAE的通过率为100%,耳闷组为90%。两组间差异有统计学意义(χ2=6.16,P<0.05)。(3)与对照组相比,耳闷患者各频率的DPOAE幅值、TEOAE的波信号噪声比(SNR)、波重复性、频段SNR及频段重复性均显著降低。差异有统计学意义(P<0.05或P<0.01)。
部分纯音听阈正常的耳闷患者存在耳蜗外毛细胞的早期损害。TEOAE和DPOAE可用于在听力损害发生前早期检测这些病变。