Kallel A, Miladi M I, Marzouk S, Feki I, Bahloul Z, Mhiri C
Service de neurologie, hôpital universitaire Habib Bourguiba, CP 3029 Sfax, Tunisie.
Rev Med Interne. 2010 Jun;31(6):e1-4. doi: 10.1016/j.revmed.2009.05.012. Epub 2010 Apr 1.
Behcet's disease (BD) is a multisystemic vasculitis. Its etiopathogeny remains unknown. Vascular involvement in BD is frequent and venous thrombosis is the most common manifestation (30% of cases). Arterial involvement is rare (2.7 to 7%). The latter is often severe and considered as a life threatening complication. Pathogenesis of thrombosis occurring in BD remains unclear. We report a 45-year-old man, from south of Tunisia, who presented a BD with a bifocal arterial involvement: right internal carotid thrombosis and bilateral proximal thrombosis of the two pulmonary arteries. Therapeutic strategies to address this multiple arterial involvement and the pathogenesis of thrombosis raise many questions.
白塞病(BD)是一种多系统血管炎。其病因仍不清楚。BD患者常出现血管受累,静脉血栓形成是最常见的表现(30%的病例)。动脉受累较少见(2.7%至7%)。后者往往较为严重,被视为危及生命的并发症。BD中发生血栓形成的发病机制仍不清楚。我们报告一名来自突尼斯南部的45岁男性,患有白塞病并伴有双灶性动脉受累:右侧颈内动脉血栓形成和双侧肺动脉近端血栓形成。针对这种多动脉受累的治疗策略以及血栓形成的发病机制引发了许多问题。