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70 至 75 岁男女的体重指数与生存率。

Body mass index and survival in men and women aged 70 to 75.

机构信息

Western Australian Centre for Health and Ageing, Centre for Medical Research, Western Australian Institute for Medical Research, The University of Western Australia, 35 Stirling Highway, Crawley, Perth, Western Australia 6009.

出版信息

J Am Geriatr Soc. 2010 Feb;58(2):234-41. doi: 10.1111/j.1532-5415.2009.02677.x.

Abstract

OBJECTIVES

To examine in an older population all-cause and cause-specific mortality associated with underweight (body mass index (BMI)<18.5), normal weight (BMI 18.5-24.9), overweight (BMI 25.0-29.9), and obesity (BMI> or =30.0).

DESIGN

Cohort study.

SETTING

The Health in Men Study and the Australian Longitudinal Study of Women's Health.

PARTICIPANTS

Adults aged 70 to 75, 4,677 men and 4,563 women recruited in 1996 and followed for up to 10 years.

MEASUREMENTS

Relative risk of all-cause mortality and cause-specific (cardiovascular disease, cancer, and chronic respiratory disease) mortality.

RESULTS

Mortality risk was lowest for overweight participants. The risk of death for overweight participants was 13% less than for normal-weight participants (hazard ratio (HR)=0.87, 95% CI=0.78-0.94). The risk of death was similar for obese and normal-weight participants (HR=0.98, 95% CI=0.85-1.11). Being sedentary doubled the mortality risk for women across all levels of BMI (HR=2.08, 95% CI=1.79-2.41) but resulted in only a 28% greater risk for men (HR=1.28 (95% CI=1.14-1.44).

CONCLUSION

These results lend further credence to claims that the BMI thresholds for overweight and obese are overly restrictive for older people. Overweight older people are not at greater mortality risk than those who are normal weight. Being sedentary was associated with a greater risk of mortality in women than in men.

摘要

目的

在老年人群中,研究体重过轻(BMI<18.5)、正常体重(BMI 18.5-24.9)、超重(BMI 25.0-29.9)和肥胖(BMI>或=30.0)与全因死亡率和死因特异性死亡率的关系。

设计

队列研究。

设置

男性健康研究和澳大利亚女性健康纵向研究。

参与者

1996 年招募的年龄在 70 至 75 岁之间的成年人,共 4677 名男性和 4563 名女性,随访时间长达 10 年。

测量

全因死亡率和死因特异性(心血管疾病、癌症和慢性呼吸道疾病)死亡率的相对风险。

结果

超重参与者的死亡率风险最低。超重参与者的死亡风险比正常体重参与者低 13%(危险比(HR)=0.87,95%置信区间(CI)=0.78-0.94)。肥胖者和正常体重者的死亡风险相似(HR=0.98,95%CI=0.85-1.11)。对于所有 BMI 水平的女性,久坐不动使死亡率风险增加一倍(HR=2.08,95%CI=1.79-2.41),但男性的风险仅增加 28%(HR=1.28(95%CI=1.14-1.44))。

结论

这些结果进一步证明,超重和肥胖的 BMI 阈值对老年人来说过于严格。超重的老年人与正常体重的人相比,死亡率风险没有增加。久坐不动与女性的死亡率风险增加有关,而与男性的死亡率风险增加无关。

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