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[日本接受异基因造血干细胞移植患者的长期随访]

[Long-term follow-up of patients undergoing allogeneic hematopoietic stem cell transplantation in Japan].

作者信息

Hagiwara Shotaro, Mochizuki Tomomi, Kondo Miki, Mori Ayako, Fukuda Takahiro

机构信息

Division of Hematology, Internal Medicine, Toyama Hospital International Medical Center of Japan.

出版信息

Rinsho Ketsueki. 2010 Mar;51(3):167-73.

Abstract

The number of hematopoietic stem cell transplantations and recipients with late complications from transplantation are both increasing; therefore, we investigated the status of the long-term follow-up system for hematopoietic stem cell transplantation survivors in Japan using a mail questionnaire; 100 of 194 institutions replied. The median examination time for each patient was 12.5 min. Five percent of institutions had an outpatient transplantation clinic, 1% had a manual for long-term follow-up after stem cell transplantation, and 11% used NIH criteria for the diagnosis of chronic GVHD. The lack of human resources, such as doctors, nurses, and other co-medical staff for transplant patients, was a structural problem. In addition, the development of guidelines for Japanese patients and staff education are also required in the clinical process. Thus, a long-term follow-up system, training of human resources, and appropriate reallocation of funds for medical services are required.

摘要

造血干细胞移植的数量以及出现移植晚期并发症的受者数量都在增加;因此,我们通过邮寄问卷的方式调查了日本造血干细胞移植幸存者长期随访系统的状况;194家机构中有100家进行了回复。每位患者的中位检查时间为12.5分钟。5%的机构设有门诊移植诊所,1%的机构有干细胞移植后长期随访手册,11%的机构采用美国国立卫生研究院(NIH)的标准诊断慢性移植物抗宿主病(GVHD)。缺乏针对移植患者的医生、护士和其他医护人员等人力资源是一个结构性问题。此外,临床过程中还需要制定针对日本患者的指南以及开展员工教育。因此,需要一个长期随访系统、人力资源培训以及为医疗服务进行适当的资金重新分配。

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