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急性B型主动脉夹层开放手术与血管腔内修复的结果:一项回顾性观察研究

Outcome of open and endovascular repair in acute type B aortic dissection: a retrospective and observational study.

作者信息

Mastroroberto Pasquale, Onorati Francesco, Zofrea Saverio, Renzulli Attilio, Indolfi Ciro

机构信息

Department of Experimental and Clinical Medicine, Cardiovascular Surgery Unit University Magna Graecia, viale Europa, 88100 Catanzaro, Italy.

出版信息

J Cardiothorac Surg. 2010 Apr 9;5:23. doi: 10.1186/1749-8090-5-23.

Abstract

BACKGROUND

The aim of the study was to analyze surgical and endovascular results in the treatment of acute type B aortic dissection (B AAD).

METHODS

Retrospective and observational analysis with patient inclusion between January 2001-December 2008 and follow-up ranged from 2 to 96 months (median = 47.2) was performed. Out of 51 consecutive patients with B AAD, 11 (21.6%) had to undergo open surgery (OS) and 13 (25.5%) endovascular treatment (TEVAR).

RESULTS

There was a significantly difference in early mortality in the TEVAR group (0/13,0%) vs OS group (4/11,36.4%, P < 0.05) and in the incidence of paraplegia/paraparesis (OS 2,28.6% vs TEVAR 1,7.7%, P < 0.05), renal failure (OS 3, 42.8% vs TEVAR 1, 7.7%, P < 0.05), respiratory failure (OS 2,28.6% vs TEVAR 1,7.7%, P < 0.05) and cerebrovascular accident (OS 1,14.3% vs TEVAR 0,0%, P < 0.05). The late mortality at a follow-up was 30.8% (4/13) in the TEVAR group and 42.8% (3/7) in the OS group, respectively (P = not significant). The cumulative survival rate after 1, 3 and 8 years was 93%, 84%, and 69% in the TEVAR group and 86%, 71% and 57% in the OS group, respectively. Endoleaks were diagnosed in 2/13 endovascular patients (15.4%).

CONCLUSIONS

TEVAR group had a significantly reduction in early mortality and postoperative complications. No significant differences were found in terms of cumulative survival at follow-up. On this basis TEVAR could be considered an option in the treatment of these complex cases with all proper reservation especially related to the small sample sizes examined.

摘要

背景

本研究旨在分析急性B型主动脉夹层(B型主动脉夹层)的手术和血管内治疗结果。

方法

进行回顾性观察分析,纳入2001年1月至2008年12月期间的患者,随访时间为2至96个月(中位数 = 47.2个月)。在连续51例B型主动脉夹层患者中,11例(21.6%)接受了开放手术(OS),13例(25.5%)接受了血管内治疗(TEVAR)。

结果

TEVAR组与OS组相比,早期死亡率(TEVAR组0/13,0% 对比OS组4/11,36.4%,P < 0.05)、截瘫/轻瘫发生率(OS组2例,28.6% 对比TEVAR组1例,7.7%,P < 0.05)、肾衰竭(OS组3例,42.8% 对比TEVAR组1例,7.7%,P < 0.05)、呼吸衰竭(OS组2例,28.6% 对比TEVAR组1例,7.7%,P < 0.05)及脑血管意外(OS组1例,14.3% 对比TEVAR组0例,0%,P < 0.05)均存在显著差异。随访时TEVAR组的晚期死亡率为30.8%(4/13),OS组为42.8%(3/7)(P = 无显著性差异)。TEVAR组1年、3年和8年后的累积生存率分别为93%、84%和69%,OS组分别为86%、71%和57%。13例接受血管内治疗的患者中有2例(15.4%)诊断出内漏。

结论

TEVAR组早期死亡率和术后并发症显著降低。随访时累积生存率方面未发现显著差异。在此基础上,TEVAR可被视为治疗这些复杂病例的一种选择,但需保留所有适当的条件,特别是与所检查的小样本量相关的条件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/213e/2856556/728d52e5cbb6/1749-8090-5-23-1.jpg

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