胺碘酮所致甲状腺功能障碍

[Amiodarone-induced thyroid gland dysfunctions].

作者信息

Gassanov N, Dietlein M, Caglayan E, Erdmann E, Er F

机构信息

Klinik III für Innere Medizin, Herzzentrum der Universität zu Köln.

出版信息

Dtsch Med Wochenschr. 2010 Apr;135(16):807-11. doi: 10.1055/s-0030-1251935. Epub 2010 Apr 13.

DOI:10.1055/s-0030-1251935

PMID:20391312

Abstract

Amiodarone treatment affects thyroid status in about the half of patients. Amiodarone causes a wide spectrum of effects on the thyroid function including hypothyroidism and thyreotoxicosis. Amiodaron-induced thyroid dysfunction is the most reason for discontinuation of amiodaron therapy. In this report we describe amiodaron-induced thyroid dysfunction and the diagnostic and therapeutic challenges in such patients.

摘要

胺碘酮治疗会影响约半数患者的甲状腺状态。胺碘酮对甲状腺功能有广泛影响，包括甲状腺功能减退和甲状腺毒症。胺碘酮所致的甲状腺功能障碍是停用胺碘酮治疗的最主要原因。在本报告中，我们描述了胺碘酮所致的甲状腺功能障碍以及此类患者的诊断和治疗挑战。