Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
J Neuroophthalmol. 2010 Jun;30(2):132-4. doi: 10.1097/WNO.0b013e3181da9d59.
A 27-year-old pregnant woman reported progressive loss of vision. Brain MRI disclosed an intracranial mass compressing the optic nerves and chiasm with imaging features suggestive of meningioma. Because delivery was imminent, surgical removal was deferred. Within a few days after delivery, the patient noted improvement in vision. Subsequent neuro-ophthalmological evaluations documented almost complete visual recovery within 2 months postpartum. The mass was removed surgically at 10 months postpartum. It was a grade I meningioma with progesterone cell surface receptors. The patient's visual function has remained stable during a follow-up of 14 months. This is the first reported case with full visual function and MRI documentation of spontaneous postpartum visual recovery in a progesterone receptor-positive meningioma compressing the anterior visual pathway.
一位 27 岁孕妇报告视力逐渐丧失。脑部 MRI 显示颅内肿块压迫视神经和视交叉,影像学特征提示脑膜瘤。由于分娩在即,手术被推迟。分娩后几天内,患者注意到视力有所改善。随后的神经眼科评估记录显示,产后 2 个月内视力几乎完全恢复。产后 10 个月进行了手术切除。肿瘤为一级脑膜瘤,孕激素细胞表面受体阳性。患者的视力功能在 14 个月的随访中保持稳定。这是首例孕激素受体阳性脑膜瘤压迫前视路,完全视觉功能和 MRI 记录的自发产后视觉恢复的病例报告。