Department of Pathology, Shizuoka City Shimizu Hospital, Shimizu-Ku, Shizuoka, Japan.
Pathol Int. 2010 Apr;60(4):330-2. doi: 10.1111/j.1440-1827.2010.02521.x.
Fibrolipoma of the spermatic cord is extremely rare. A case of giant fibrolipoma of the right spermatic cord is reported here. A 68-year-old man noticed a mass in the right inguinal region, and was admitted to Shizuoka City Shimizu Hospital. Tumorectomy and right orchiectomy were performed. Grossly, the tumor was a well-defined, yellowish white, solid, firm tumor measuring 13 x 10 x 9 cm. The tumor had a thin capsule. The tumor was attached to the right spermatic cord, and was remote from the right testis and epididymis. Microscopically, the tumor was composed of mature adipose tissue (40% in area) and collagenous fibrous tissue (60% in area). No lipoblasts were recognized, and on immunohistochemistry the tumor was negative for MDM2 and CDK4. Neither smooth muscle nor vascular proliferation was recognized. The tumor was diagnosed as giant fibrolipoma of the right spermatic cord. To the best of the author's knowledge, only two cases of fibrolipoma in the spermatic cord, scrotum, and testis have been reported in the English-language literature.
精索纤维脂肪瘤极其罕见。本文报告 1 例右侧精索巨大纤维脂肪瘤。1 例 68 岁男性患者发现右侧腹股沟区有一肿块,遂入住静冈市清水医院。行肿瘤切除术和右侧睾丸切除术。大体上,肿瘤界限清楚,呈淡黄色,灰白色,实性,质地坚硬,大小为 13 x 10 x 9 cm。肿瘤有一薄包膜。肿瘤附着于右侧精索,远离右侧睾丸和附睾。镜下,肿瘤由成熟脂肪组织(占 40%)和胶原纤维组织(占 60%)组成。未见脂肪母细胞,免疫组化肿瘤 MDM2 和 CDK4 均为阴性。未见平滑肌或血管增生。诊断为右侧精索巨大纤维脂肪瘤。据作者所知,在英文文献中仅报道过 2 例发生于精索、阴囊和睾丸的纤维脂肪瘤。