Department of Physiology, University of California, San Francisco, CA 94158, USA.
Cell. 2010 Apr 16;141(2):224-6. doi: 10.1016/j.cell.2010.03.042.
The cell divides in a series of discrete steps that occur in a specific order. Lu and Cross (2010) now propose that cell-cycle events are ordered by a regulatory system in which a master oscillator, based on cyclin-dependent kinases, entrains a series of peripheral oscillators controlling individual events.
细胞在一系列特定顺序发生的离散步骤中进行分裂。Lu 和 Cross(2010)现在提出,细胞周期事件是由一个基于细胞周期蛋白依赖性激酶的主振荡器控制的调节系统有序排列的,该系统使一系列控制单个事件的外围振荡器同步。