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一种新型微创外科手术举宫系统:“Laparo-V”免气腹与 CO2 气腹腹腔镜结直肠手术的前瞻性比较。

A novel lifting system for minimally accessed surgery: a prospective comparison between "Laparo-V" gasless and CO2 pneumoperitoneum laparoscopic colorectal surgery.

机构信息

Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China.

出版信息

Int J Colorectal Dis. 2010 Aug;25(8):997-1004. doi: 10.1007/s00384-010-0942-5. Epub 2010 Apr 21.

Abstract

PURPOSE

Carbon dioxide (CO(2)) pneumoperitoneum can lead to cardiopulmonary loading and complications. By comparing with conventional CO(2) pneumoperitoneum approach, we introduce a novel Laparo-V lifting system for gasless laparoscopic colorectal surgery.

METHODS

In a prospective study, patients with colonic lesions underwent either Laparo-V gasless (n = 20) or conventional CO(2) pneumoperitoneum (n = 19) laparoscopic colectomy. Twenty patients who underwent open surgery were enrolled as control. Intra-operative monitoring includes blood pressures, heart rate, O(2) saturation, and end-tidal CO(2) (ET-CO(2)). Serum level of interleukin 6 (IL-6), C-reactive protein (CRP), cortisol, and lymphocyte subpopulations (CD4/CD8) were measured repeatedly. Postoperative recovery was indicated by return of bowel function and postoperative hospital stay.

RESULTS

Patient characteristics were not different between the three groups. There were three conversions in each laparoscopy group, making conversion rates 15% and 15.7% for Laparo-V and CO(2) pneumoperitoneum groups, respectively. Vital signs remained stable in Laparo-V and open surgery groups; while, elevated ET-CO(2) and heart rate were noted in CO(2) pneumoperitoneum group. Both laparoscopy groups had a significant faster recovery and shorter hospital stay than the open surgery group. Postoperative elevation of IL-6, CRP, and cortisol level was observed in all the three groups, of note, the change was most significant in the open surgery group.

CONCLUSIONS

Laparo-V gasless laparoscopic approach is feasible in various colorectal procedures. It carries advantages comparable with those of CO(2) pneumoperitoneum; while, the intra-operative hemodynamic was more stable. Therefore, laparoscopic approach using the Laparo-V system could be beneficial to patients with high cardiopulmonary risk and represents an alternative for minimally invasive surgery.

摘要

目的

二氧化碳(CO2)气腹可导致心肺负荷增加和并发症。通过与传统的 CO2 气腹方法比较,我们为无气腹腹腔镜结直肠手术引入了一种新的拉帕罗-V 提升系统。

方法

在一项前瞻性研究中,患有结肠病变的患者接受了拉帕罗-V 无气腹(n = 20)或传统 CO2 气腹(n = 19)腹腔镜结肠切除术。20 例接受开放手术的患者被纳入对照组。术中监测包括血压、心率、血氧饱和度和呼气末 CO2(ET-CO2)。反复测量血清白细胞介素 6(IL-6)、C 反应蛋白(CRP)、皮质醇和淋巴细胞亚群(CD4/CD8)水平。术后恢复情况以肠道功能恢复和术后住院时间表示。

结果

三组患者的特征无差异。每个腹腔镜组都有 3 例转为开放手术,拉帕罗-V 和 CO2 气腹组的转化率分别为 15%和 15.7%。拉帕罗-V 和开放手术组的生命体征保持稳定;而 CO2 气腹组则出现 ET-CO2 和心率升高。与开放手术组相比,拉帕罗-V 和腹腔镜组的恢复更快,住院时间更短。三组患者术后均出现 IL-6、CRP 和皮质醇水平升高,值得注意的是,开放手术组的变化最为显著。

结论

拉帕罗-V 无气腹腹腔镜方法适用于各种结直肠手术。它具有与 CO2 气腹相当的优势;而术中血流动力学更稳定。因此,使用拉帕罗-V 系统的腹腔镜方法可能对心肺风险较高的患者有益,并代表了微创外科的一种替代方法。

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