Madjar H, Becker S, Doubek K, Horchler T, Mendoza M, Moisidis-Tesch C, Näther B, Niebling K, Pröls U, Schardt A-R, Ulrich S, Zahn U
Gynäkologie, DKD, Wiesbaden.
Ultraschall Med. 2010 Jun;31(3):289-95. doi: 10.1055/s-0028-1110010. Epub 2010 Apr 20.
To define the value of whole breast ultrasound for breast cancer detection in primary women's health care in gynecological routing practice.
Among women who were operated at the breast center of the German Diagnostic Clinic (DKD) in the year 2007, we selected different indications for the examinations which were relevant for the detection of breast lesions.
Twenty-one of 86 breast cancers (24 %) which were treated at the DKD in the year 2007 were detected only because of an individual ultrasound screening examination. None of these women had abnormal clinical findings and only 8 of these women had abnormal mammograms. The majority of these cancers were early stages, pT1a/b. In this group of patients, only 8 benign lesions detected by ultrasound were operated. This corresponds to a ratio of benign vs. malignant operations of 0.4 to 1, which is far superior to the recommendations of international guidelines for quality assurance.
Our results show that ultrasound screening considerably increases the detection of early breast cancers without increasing the rate of unnecessary biopsies. This should encourage gynecologists to learn and perform systematic breast ultrasound examinations and to increase their own performance by continuous training. We can expect that additional studies will prove breast ultrasound to be a powerful method for improving breast cancer detection. Currently available state-of-the-art ultrasound technology allows for early detection, but further education and quality control are important for implementation in nation-wide health care.
确定在妇科日常诊疗的初级妇女保健中,全乳超声对乳腺癌检测的价值。
在2007年于德国诊断诊所(DKD)乳腺中心接受手术的女性中,我们选择了与乳腺病变检测相关的不同检查指征。
2007年在DKD接受治疗的86例乳腺癌中,有21例(24%)仅通过个体超声筛查检查被发现。这些女性均无异常临床体征,且其中只有8例女性乳房X线照片异常。这些癌症大多处于早期,pT1a/b期。在这组患者中,仅对超声检测出的8例良性病变进行了手术。这对应着良性与恶性手术的比例为0.4比1,远优于国际质量保证指南的建议。
我们的结果表明,超声筛查可显著提高早期乳腺癌的检出率,而不会增加不必要活检的比率。这应促使妇科医生学习并开展系统性乳腺超声检查,并通过持续培训提高自身业务水平。我们预计,更多研究将证明乳腺超声是改善乳腺癌检测的有力方法。目前可用的先进超声技术能够实现早期检测,但继续教育和质量控制对于在全国范围内的医疗保健中实施该技术至关重要。