Department of Pure and Applied Chemistry in Faculty of Science and Technology and Research Institute of Science and Technology, Tokyo University of Science, Noda, Chiba 278-8510, Japan.
Colloids Surf B Biointerfaces. 2010 Aug 1;79(1):205-9. doi: 10.1016/j.colsurfb.2010.03.051. Epub 2010 Apr 7.
We have studied friction forces on binary mixtures of phospholipid monolayer films. The phospholipid monolayer films have been prepared via the Langmuir-Blodgett (LB) technique on mica. The two-component phospholipids are distearoylphosphatidylcholine (DSPC) and dilauroylphosphatidylcholine (DLPC). At 25 degrees C the LB monolayer films give the gel-state DSPC domains surrounded by the liquid crystalline DLPC matrix. The friction forces measured on the DSPC domain region are significantly greater than those on the DLPC matrix region at this temperature. An increased temperature results in a decreased friction of the DSPC domain region, and above the gel-to-liquid crystalline phase transition temperature of DSPC, the difference in the friction forces measured on the two phospholipids becomes negligible. This means that the phase state is a key factor in determining friction forces on the phospholipid monolayer films.
我们研究了磷脂单分子膜双层混合物的摩擦力。通过 Langmuir-Blodgett (LB) 技术在云母上制备了磷脂单分子膜。两种磷脂分别为二硬脂酰磷脂酰胆碱（DSPC）和二月桂酰磷脂酰胆碱（DLPC）。在 25°C 时，LB 单分子膜呈现出由液晶态 DLPC 基质包围的凝胶态 DSPC 区域。在该温度下，测量到 DSPC 区域的摩擦力明显大于 DLPC 基质区域的摩擦力。升高温度会降低 DSPC 区域的摩擦力，并且在 DSPC 的凝胶到液晶相转变温度以上，测量到的两种磷脂的摩擦力差异变得可以忽略不计。这意味着相态是决定磷脂单分子膜摩擦力的关键因素。
