Division of Cardiology, 2nd University of Naples, 'Monaldi' Hospital, Naples, Italy.
J Cardiovasc Med (Hagerstown). 2010 Nov;11(11):852-7. doi: 10.2459/JCM.0b013e32833a070d.
Despite current trends toward primary repair, surgical systemic-to-pulmonary shunt is still an invaluable palliative option in some patients with congenital heart defects and duct-dependent pulmonary circulation. However, arterial duct stabilization with a high-flexibility coronary stent could be an effective alternative in high-risk surgical candidates or whenever short-term pulmonary blood flow support is anticipated.
On the basis of ductal origin and morphology, the stenting procedure can be performed from an arterial or venous route. Following arterial duct angiographic imaging, the stabilizing stent is chosen to completely cover the entire ductal length and dilated slightly less than the proposed surgical shunt. Procedural failure depends mainly on ductal tortuosity and ranges around 10% of cases. Morbidity and mortality are 8-11% and less than 1%, respectively. Mid-term fate of the stented duct is spontaneous, slow and progressive closure within a few months. Compared with a Blalock-Taussig shunt, stented ducts result in similar but more uniform pulmonary artery growth over a mid-term follow-up.
Arterial duct stenting is a technically feasible, well tolerated and effective palliation in congenital heart disease with duct-dependent pulmonary circulation. It is advisable either in high-risk neonates or whenever a short-term pulmonary blood flow support is anticipated. The stented duct appears less durable than a conventional surgical shunt although it is highly effective in promoting a global and uniform pulmonary artery growth.
尽管目前有向主修复的趋势,但在某些患有先天性心脏缺陷和依赖导管的肺循环的患者中,外科体肺分流术仍然是一种非常宝贵的姑息治疗选择。然而,对于高风险的手术候选者或预计短期肺动脉血流支持时,带有高柔韧性冠状动脉支架的动脉导管稳定术可能是一种有效的替代方法。
根据导管的起源和形态,可以从动脉或静脉途径进行支架置入术。在进行动脉导管血管造影成像后,选择稳定支架完全覆盖整个导管长度,并稍微扩张至略小于拟议的外科分流术。程序失败主要取决于导管的扭曲程度,约占病例的 10%。发病率和死亡率分别为 8-11%和小于 1%。支架置入后的中期命运是自发性的,在几个月内缓慢而逐渐地闭合。与 Blalock-Taussig 分流术相比,支架置入后的导管在中期随访中导致类似但更均匀的肺动脉生长。
动脉导管支架置入术是一种技术上可行、耐受性良好且有效的姑息治疗方法,适用于依赖导管的肺循环的先天性心脏病。对于高危新生儿或预计短期肺动脉血流支持时,建议使用该方法。支架置入后的导管似乎不如传统的外科分流术持久,但它在促进整体和均匀的肺动脉生长方面非常有效。