Martínez-Quiñones J V, Aso-Escario J, Consolini F, Arregui-Calvo R
Hospital MAZ, Zaragoza.
Neurocirugia (Astur). 2010 Apr;21(2):108-17.
The intervertebral disc disease (IDD) is one of the most common muscle-skeletal disorders, causing both high work disability and elevated healthcare costs. There are two specific origins of disk disease that should be kept in mind: degenerative (DDD) and traumatic (TDD). Concerning the TDD, nowadays it has not been determined which patients could gradually improve and which ones will require surgery. Some studies indicate that about 85% of lumbar and 90% cervical acute disc herniation will get better in an average of 6 weeks.
We conducted an observational, prospective study, over a group of 858 patients, with the following inclusion criteria: 1. MRI imaging indicating TDD, 2. No signs or symptoms requiring urgent surgical treatment (cauda equina syndrome, progressive or serious motor deficit or unbearable pain) and 3. Development of progressively spontaneous symptoms remission. All of the patients included in our study were treated in our Department of Neurosurgery from 2006 to 2007. Patients were tested for disc herniation regression with a second MRI study.
A spontaneous regression of their hernia was appreciated as follow: 33 cases of lumbar hernia (29 male, 4 female), 3 cervical hernia (1 male, 2 female) and 1 dorsal hernia (male).
Research about other reported series was done, and the different factors that could take place in disc spontaneous regression were analyzed: a) lodgement of the herniated disc back into the intervertebral space; b) disappearance of the herniated fragment due to dehydration and retraction mechanisms; c) gradual resorption of the herniated tissue by phagocytosis and enzymatic degradation induced by an inflammatory reaction that appeared as the disc (acting the extrusion itself as an foreign body) and, d) pulsion of cephaloarchidian liquid against the herniated portion.
Disc herniation can regress, or even disappear, in a number of patients, rendering the radiological findings not to be taken as the only surgical indication criterium. We consider that the best treatment is the one relying on a good doctor-patient relationship, suspended in a balance between conservative and surgical treatment. According to clinical data, the first one (conservative) should not exceed the estimated time beyond which the surgical result would be unsatisfactory. The second one (operative), excepting "need-to operate" situations (such as cauda equina compression, progressive or serious motor déficit, or unbearable pain), should be prudently supedited to MRI regresión control, in particular in patients in which a clinical improvement is observed. Thus, the disc herniation conservative healing, both clinical as radiological, do exist, being a concept to widespread among clinicians and patients also.
椎间盘疾病(IDD)是最常见的肌肉骨骼疾病之一,导致高工作残疾率和医疗成本上升。椎间盘疾病有两个特定起源应牢记:退行性(DDD)和创伤性(TDD)。关于TDD,目前尚未确定哪些患者可逐渐改善,哪些患者需要手术。一些研究表明,约85%的腰椎和90%的颈椎急性椎间盘突出症平均在6周内会好转。
我们对一组858例患者进行了一项观察性前瞻性研究,纳入标准如下:1. MRI成像显示TDD;2. 无需要紧急手术治疗的体征或症状(马尾综合征、进行性或严重运动功能障碍或无法忍受的疼痛);3. 出现逐渐自发的症状缓解。我们研究纳入的所有患者均于2006年至2007年在我们的神经外科接受治疗。通过第二次MRI研究对患者的椎间盘突出症消退情况进行检测。
观察到其疝的自发消退情况如下:33例腰椎疝(男性29例,女性4例),3例颈椎疝(男性1例,女性2例),1例胸椎疝(男性)。
对其他报道系列进行了研究,并分析了可能导致椎间盘自发消退的不同因素:a)突出的椎间盘回纳到椎间隙;b)由于脱水和回缩机制,突出碎片消失;c)通过吞噬作用和炎症反应诱导的酶降解逐渐吸收突出组织,炎症反应是椎间盘突出(突出本身起异物作用)引发的;d)脑脊液对突出部分的冲击。
在一些患者中,椎间盘突出症可消退甚至消失,这使得影像学检查结果不能作为唯一的手术指征标准。我们认为最佳治疗方法是建立良好的医患关系,在保守治疗和手术治疗之间保持平衡。根据临床数据,第一种(保守治疗)不应超过估计时间,超过该时间手术结果可能不理想。第二种(手术治疗),除“必须手术”的情况(如马尾神经受压、进行性或严重运动功能障碍或无法忍受的疼痛)外,应谨慎地等待MRI消退控制,特别是在观察到临床改善的患者中。因此,椎间盘突出症的保守愈合,无论是临床还是影像学上,都是存在的,这一概念也应在临床医生和患者中广泛传播。