Chiummariello S, Iera M, Domatsoglou A, Alfano C
Department of Plastic Surgery, University of Perugia.
G Chir. 2010 Apr;31(4):191-6.
The benefits and superiority of free flaps for head and neck reconstruction are well recognized. However, in some instances, especially in elderly and critical patients with advanced intraoral and oropharyngeal cancers or in patients with underlying systemic syndromes (i.e. uncontrolled diabetes, cardio-pulmonary failure, renal insufficiency), the use of pectoralis mayor myocutaneous flap may be a preferable option with fewer risks for the patient.
We present a series of 12 pectoralis major myocutaneous flaps, performed from January 2007 to June 2008, in 12 critical patients who presented with advanced carcinomas of the oral cavity and oropharynx. In all cases, histology showed (T3-T4)-(N0-N3)-M0 squamous cell carcinomas. Tumors were: 4 intraoral (33%), 2 in the oropharynx (16%), 5 in the hypopharynx (41%) and 1 of the skin left auricle (8%).
There were no flap loss. Partial skin necrosis (<10%) occurred in 1 case (8%); one patient (8%) developed wound infection treated successfully with systemic antibiotic therapy. Minor oro cutaneous fistulas developed in 2 patients (16%). At the follow-up 4 patients (34%) died after 4 months, 2 patients (16%) had recurrence of disease, 6 patients (50%) showed no evidence of disease.
The use of pectoralis major myocutaneous flap as a salvage procedure in immediate reconstruction following ablative surgery of head and neck cancers is still a valid alternative procedure to free tissue transfer. Because of reduced operative times, reduced anaesthetic risk, reduced risk of total flap necrosis and reduced costs, it could be considered as a preferable choice in selected cases.
游离皮瓣用于头颈部重建的益处和优势已得到广泛认可。然而,在某些情况下,尤其是老年患者以及患有晚期口腔和口咽癌的重症患者,或患有潜在全身综合征(如未控制的糖尿病、心肺功能衰竭、肾功能不全)的患者,胸大肌肌皮瓣的使用可能对患者来说风险更小,是更可取的选择。
我们报告了2007年1月至2008年6月期间为12例患有晚期口腔和口咽癌的重症患者实施的12例胸大肌肌皮瓣手术。所有病例的组织学检查均显示为(T3 - T4)-(N0 - N3)- M0期鳞状细胞癌。肿瘤分布情况为:口腔内4例(33%),口咽2例(16%),下咽5例(41%),左耳皮肤1例(8%)。
未出现皮瓣丢失情况。1例(8%)发生部分皮肤坏死(<10%);1例患者(8%)出现伤口感染,经全身抗生素治疗成功治愈。2例患者(16%)出现轻微口皮瘘。随访时,4例患者(34%)在4个月后死亡,2例患者(16%)疾病复发,6例患者(50%)无疾病迹象。
胸大肌肌皮瓣作为头颈部癌症切除术后即刻重建的挽救性手术方法,仍然是游离组织移植的有效替代方法。由于手术时间缩短、麻醉风险降低、皮瓣完全坏死风险降低以及成本降低,在某些特定病例中可将其视为更可取的选择。