Division of Neurology, Department of Medicine, Thammasat University, Bangkok, Thailand.
J Stroke Cerebrovasc Dis. 2010 Sep-Oct;19(5):353-6. doi: 10.1016/j.jstrokecerebrovasdis.2009.06.008. Epub 2010 May 4.
Crescendo transient ischemic attacks (TIAs) are defined as repeated frequent short-lasting episodes of focal neurologic deficit due to cerebral ischemia. The capsular warning syndrome, a subset of crescendo TIA, consists of repetitive episodes of motor dysfunction due to ischemia in the region of internal capsule. It is not clear that patients with ischemia in the pons can have a similar clinical presentation and course. We report 11 cases presenting with crescendo TIA in the form of pure motor hemiparesis or ataxic hemiparesis that later proved to have a paramedian pontine infarct. The presumed mechanism of these infarcts is penetrating basilar artery branch occlusion at their origin, also called basilar branch disease.
渐强型短暂性脑缺血发作(TIA)定义为由于脑缺血导致的反复发作的短暂性局灶性神经功能缺损。壳核预警综合征是渐强型 TIA 的一个亚型,由内囊区域缺血引起的反复发作的运动功能障碍组成。目前尚不清楚脑桥缺血的患者是否会出现类似的临床表现和病程。我们报告了 11 例以纯运动性偏瘫或共济失调性偏瘫形式出现的渐强型 TIA 病例,后来证实这些病例患有旁正中脑桥梗死。这些梗死的推测机制是起源处穿透基底动脉分支闭塞,也称为基底动脉分支疾病。