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低体重指数和低血清白蛋白是需要家庭护理的日本老年患者短期死亡的预测因素。

Low body mass index and low serum albumin are predictive factors for short-term mortality in elderly Japanese requiring home care.

机构信息

Department of Nursing, Niigata University of Health and Welfare, Niigata, Japan.

出版信息

Tohoku J Exp Med. 2010 May;221(1):29-34. doi: 10.1620/tjem.221.29.

Abstract

Japan has a rapidly growing elderly population requiring care. This study aimed to clarify risk factors for two-year mortality in such people. Subjects included 205 community-dwelling elderly people, who were approved for care in the 2003 Yamato Study, an epidemiologic study of individuals utilizing the long-term care service system. Demographic characteristics, Barthel index (measuring activities of daily living), grip strength, thigh muscle volume, psychological evaluation, and blood values including hemoglobin, serum albumin, and serum 25-hydroxyvitamin D levels were investigated at baseline. The average age of subjects was 83.6 (S.D., 8.0) years. Of the 205 subjects, 42 died during the follow-up period. Bivariate analysis showed that older age (p = 0.0015), lower weight (p = 0.0087), lower body mass index (BMI) (p = 0.0001), lower Barthel index (p = 0.0017), lower hemoglobin (p = 0.0180), and lower serum albumin (p = 0.0001) were associated with mortality, but that sex was not (p = 0.1248). Stepwise multiple logistic regression analysis showed that BMI < 17.1 kg/m(2) (adjusted OR = 4.0, p = 0.0007), age >or= 90 years (adjusted OR = 3.3, p = 0.0033), and lower serum albumin levels (adjusted OR = 0.86, p = 0.0007) were independently associated with mortality. We conclude that low BMI and low serum albumin are strong predictors of 2-year mortality in frail elderly individuals, and that nutritional risk should appropriately be evaluated for elderly people requiring home care.

摘要

日本的老年人口迅速增长,需要护理。本研究旨在阐明此类人群两年死亡率的危险因素。研究对象包括 205 名居住在社区的老年人,他们在 2003 年大和研究中被批准接受长期护理服务。该研究是一项对使用长期护理服务系统的个体进行的流行病学研究。在基线时调查了人口统计学特征、巴氏指数(测量日常生活活动能力)、握力、大腿肌肉量、心理评估以及血红蛋白、血清白蛋白和血清 25-羟维生素 D 水平等血液值。受试者的平均年龄为 83.6(S.D.,8.0)岁。在 205 名受试者中,有 42 人在随访期间死亡。双变量分析显示,年龄较大(p = 0.0015)、体重较低(p = 0.0087)、体重指数(BMI)较低(p = 0.0001)、巴氏指数较低(p = 0.0017)、血红蛋白较低(p = 0.0180)和血清白蛋白较低(p = 0.0001)与死亡率相关,但性别无关(p = 0.1248)。逐步多变量逻辑回归分析显示,BMI<17.1 kg/m2(调整后的 OR = 4.0,p = 0.0007)、年龄≥90 岁(调整后的 OR = 3.3,p = 0.0033)和较低的血清白蛋白水平(调整后的 OR = 0.86,p = 0.0007)与死亡率独立相关。我们的结论是,低 BMI 和低血清白蛋白是体弱老年人两年死亡率的强有力预测因素,对于需要家庭护理的老年人,应适当评估营养风险。

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