Department of Periodontology, Center for Dental, Oral, and Maxillofacial Medicine (Carolinum), Johann Wolfgang Goethe-University Frankfurt am Main, D-60590 Frankfurt am Main, Germany.
J Periodontol. 2010 Jun;81(6):827-36. doi: 10.1902/jop.2010.090632.
This study clinically evaluates the 10-year results of connective tissue graft (CTG) and guided tissue regeneration (GTR) therapies using bioabsorbable barriers for root coverage (i.e., the reduction of recession depth).
In 15 patients, 38 Miller Class I and II recessions were treated. Recession defects received a CTG or GTR by random assignment. At baseline (immediately prior to surgery) and 6 and 120 +/- 12 months after surgery, clinical parameters were obtained.
Nine patients, who contributed 24 recession defects, were available for re-examination at 120 +/- 12 months. Six and 120 +/- 12 months after receiving a CTG, statistically significant (P <0.05) root coverage was observed compared to baseline root coverage (6 months: 3.07 +/- 1.74 mm; 120 +/- 12 months: 2.07 +/- 1.89 mm). The GTR therapy resulted in statistically significant root coverage compared to baseline root coverage only after 6 months (2.28 +/- 1.77 mm; P <0.05). Both groups experienced a statistically significant loss of coverage from 6 to 120 +/- 12 months (CTG: -1.0 +/- 0.78 mm; GTR: -2.03 +/- 2.24 mm). At 120 +/- 12 months after CTG surgery, the stability of root coverage was statistically significantly better than 120 +/- 12 months after GTR surgery (P = 0.002). The CTG caused more post-surgical discomfort (P <0.05), but it resulted in a better treatment outcome (P <0.05) than GTR as perceived by patients.
The long-term stability of root coverage (i.e., the reduction of recession depth) and esthetic results perceived by patients were significantly better 10 years after CTG surgery, statistically, than after GTR surgery using bioabsorbable barriers.
本研究通过临床评估使用可吸收屏障进行根覆盖(即减少退缩深度)的 10 年结缔组织移植物(CTG)和引导组织再生(GTR)治疗的 10 年结果。
在 15 名患者中,治疗了 38 例米勒 I 类和 II 类退缩。退缩缺陷通过随机分配接受 CTG 或 GTR。在基线(手术前立即)和手术后 6 个月和 120 +/- 12 个月时获得临床参数。
9 名患者(共 24 个退缩缺陷)在 120 +/- 12 个月时可重新检查。与基线根覆盖相比,接受 CTG 后 6 个月和 120 +/- 12 个月时观察到统计学上显著(P <0.05)的根覆盖(6 个月:3.07 +/- 1.74 毫米;120 +/- 12 个月:2.07 +/- 1.89 毫米)。GTR 治疗仅在 6 个月后与基线根覆盖相比具有统计学上显著的根覆盖(2.28 +/- 1.77 毫米;P <0.05)。两组在 6 至 120 +/- 12 个月期间均经历了统计学上显著的覆盖丧失(CTG:-1.0 +/- 0.78 毫米;GTR:-2.03 +/- 2.24 毫米)。在 CTG 手术后 120 +/- 12 个月时,根覆盖的稳定性统计学上显著优于 GTR 手术后 120 +/- 12 个月(P = 0.002)。CTG 术后引起的不适(P <0.05)更多,但患者认为 CTG 治疗结果(P <0.05)优于 GTR。
在 CTG 手术后 10 年,与使用可吸收屏障的 GTR 手术相比,通过临床评估,根覆盖(即减少退缩深度)的长期稳定性和患者感知的美学效果在统计学上显著更好。