二叶式主动脉瓣患者的主动脉是否真的应该比三叶式更早切除？赞成。

Should aortas in patients with bicuspid aortic valve really be resected at an earlier stage than tricuspid? PRO.

机构信息

Department of Cardiothoracic Surgery, Hadassah Medical Center, Hebrew University, Ein-Kerem, PO Box 12000, Jerusalem 91120, Israel.

出版信息

Cardiol Clin. 2010 May;28(2):289-98. doi: 10.1016/j.ccl.2010.01.005.

DOI:10.1016/j.ccl.2010.01.005

PMID:20452544

Abstract

Bicuspid aortic valve (BAV) is the most frequently occurring congenital cardiac anomaly, affecting 1% to 2% of the population. BAV disease is increasingly recognized as a disease of the entire proximal aorta up to the level of the ligamentum arteriosum. The recent unfolding of the genetic and biologic background of the disease and the accumulating data regarding the natural history of BAV-associated aortic dilatation have accrued multiple levels of evidence strongly supporting early surgical intervention.

摘要

二叶式主动脉瓣（BAV）是最常见的先天性心脏畸形，影响 1%至 2%的人口。BAV 疾病越来越被认为是整个近端主动脉的疾病，直至动脉韧带水平。该疾病的遗传和生物学背景的最新发展以及关于 BAV 相关主动脉扩张的自然病史的累积数据，积累了多个层面的证据，强烈支持早期手术干预。