Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA.
Dalton Trans. 2010 Aug 7;39(29):6726-31. doi: 10.1039/c001927e. Epub 2010 May 10.
A comparison between the reactivity behavior of two lutetium benzyl complexes supported by different ferrocene-diamide ligands towards aromatic N-heterocycles, such as 1-methylimidazole, isoquinoline, and pyridines, is presented. The two ferrocene-diamide ancillary ligands differ in their nitrogen-donor substituent: adamantyl for one and t-butyldimethylsilyl for the other. The synthesis and characterization of the adamantyl-derived complex 1(Ad)-DME are reported. The ring opening of 1-methylimidazole by the THF analogue of 1(Ad)-DME, 1(Ad)-THF, was observed, analogously to the ring opening of the same substrate by the lutetium benzyl complex supported by the silyl-substituted ligand. Also, analogous products were observed in the reactions with isoquinoline.
介绍了两种由不同二茂铁二酰胺配体支撑的镥芐基配合物对芳香族 N-杂环化合物（如 1-甲基咪唑、异喹啉和吡啶）的反应性行为的比较。这两个二茂铁二酰胺辅助配体在其氮供体取代基上有所不同：一个是金刚烷基，另一个是叔丁基二甲基硅基。报道了金刚烷基衍生的配合物 1(Ad)-DME 的合成和表征。观察到 1-甲基咪唑被 1(Ad)-DME 的 THF 类似物 1(Ad)-THF 开环，类似于由取代基为硅基的配体支撑的镥芐基配合物对相同底物的开环。同样，在与异喹啉的反应中也观察到了类似的产物。
