Castle David, Schweitzer Isaac, Tiller John
Department of Psychiatry, The University of Melbourne, St Vincent's Health, Fitzroy, VIC, Australia.
Australas Psychiatry. 2009;17(5):360-4. doi: 10.1080/10398560903176958.
The aim of this paper was to review the large US National Institute of Mental Health-sponsored depression intervention effectiveness study, STAR*D, in order to evaluate critically its relevance for Australasian clinicians.
STAR*D is a landmark study which tried to address issues of effectiveness rather than efficacy, of a number of interventions for depression. However, methodological shortcomings limit the utility of the study in informing Australasian clinical practice.