Genetics Laboratory, Institute of Biological Problems of the North, Far-East Branch of Russian Academy of Sciences, Magadan, Russia.
Mol Biol Evol. 2010 Oct;27(10):2220-6. doi: 10.1093/molbev/msq065. Epub 2010 May 10.
To investigate diversity of mitochondrial gene pool of Tatars inhabiting the territory of the middle Volga River basin, 197 individuals from two populations representing Kazan Tatars and Mishars were subjected for analysis of mitochondrial DNA (mtDNA) control region variation. In addition, 73 mitochondrial genomes of individuals from Mishar population were sequenced completely. It was found that mitochondrial gene pool of the Volga Tatars consists of two parts, but western Eurasian component prevails considerably (84% on average) over eastern Asian one (16%). Eastern Asian mtDNAs detected in Tatars belonged to a heterogeneous set of haplogroups (A, C, D, G, M7, M10, N9a, Y, and Z), although only haplogroups A and D were revealed simultaneously in both populations. Complete mtDNA variation study revealed that the age of western Eurasian haplogroups (such as U4, HV0a, and H) is less than 18,000 years, thus suggesting re-expansion of eastern Europeans soon after the Last Glacial Maximum.
为了研究居住在中伏尔加河流域的鞑靼人的线粒体基因库的多样性，对来自代表喀山鞑靼人和米沙尔人的两个群体的 197 个人进行了线粒体 DNA（mtDNA）控制区变异分析。此外，米沙尔人群的 73 个线粒体基因组被完全测序。研究发现，伏尔加鞑靼人的线粒体基因库由两部分组成，但西方欧亚成分明显占主导地位（平均占 84%），而东亚成分仅占 16%。在鞑靼人中检测到的东亚线粒体 DNA 属于一组异质的单倍群（A、C、D、G、M7、M10、N9a、Y 和 Z），尽管这两个群体同时只显示了单倍群 A 和 D。完整的 mtDNA 变异研究表明，西方欧亚单倍群（如 U4、HV0a 和 H）的年龄小于 18000 年，这表明末次冰盛期后东欧人的重新扩张。
