Volkov V S, Rudenko E V
State Medical Academy, ul. Sovetskaya 4, 170642 Tver, Russia.
Kardiologiia. 2010;50(3):47-50.
With the aim of studying linear velocity characteristics of arteriolar blood flow and reactivity of arterioles we examined 80 patients with essential arterial hypertension (AH), 83 patients with type 2 diabetes mellitus (DM) with concomitant AH, and 63 healthy people. In all patients examination included ultrasound continuous wave dopplerography of microcirculatory vascular bed at rest and after distant warming test. It was found that in patients with essential AH blood flow velocity in arterioles was maximal, increment of arteriolar blood flow in response to warming was lower than in healthy persons. In patients with type 2 DM minimal linear velocity characteristics of arteriolar blood flow and its increment in response to warming test were minimal. Results of the study evidence for principal differences of functioning and reactivity of arterioles in patients with essential AH and AH developed at the background of diabetes mellitus.
为了研究小动脉血流的线性速度特征和小动脉的反应性,我们检查了80例原发性动脉高血压(AH)患者、83例伴有AH的2型糖尿病(DM)患者和63名健康人。对所有患者的检查包括在静息状态下以及远隔部位温热试验后,采用超声连续波多普勒成像技术对微循环血管床进行检测。结果发现,原发性AH患者的小动脉血流速度最高,温热刺激后小动脉血流的增加幅度低于健康人。2型DM患者小动脉血流的线性速度特征及温热试验后血流增加幅度最小。该研究结果证明了原发性AH患者与糖尿病背景下发生的AH患者小动脉功能和反应性存在主要差异。