Scrimshaw Nevin S, Viteri Fernando E
International Nutrition Foundation, USA.
Food Nutr Bull. 2010 Mar;31(1):34-41. doi: 10.1177/156482651003100105.
This article summarizes thirty years of intensive clinical metabolic and therapeutic studies of the consequences of severe protein deficiency relative to calories, which results in kwashiorkor, and of a balanced deficiency of protein and calories that results in marasmus. Evidence is provided that these are two different metabolic diseases, but kwashiorkor is usually superimposed on some degree of chronic marasmus and hence most cases studied were marasmic kwashiorkor. The value of the creatinine/height index to indicate the degree of lean body cell mass with any disease is demonstrated.
本文总结了三十年来针对严重蛋白质缺乏（相对于热量）导致夸希奥科病，以及蛋白质和热量均衡缺乏导致消瘦症的后果所进行的深入临床代谢和治疗研究。有证据表明这是两种不同的代谢疾病，但夸希奥科病通常叠加在某种程度的慢性消瘦症之上，因此大多数研究的病例是消瘦型夸希奥科病。文中展示了肌酐/身高指数在指示任何疾病中瘦体细胞群程度方面的价值。
