Kubo S, Arakawa T, Nakajo H, Nomura K, Ishida H, Irie A, So S, Rokkaku S, Iwamura M, Kasai I
Department of Urology, Sagamidai Hospital.
Nihon Hinyokika Gakkai Zasshi. 1991 Jan;82(1):102-9. doi: 10.5980/jpnjurol1989.82.102.
Thirty patients (16 men and 14 women) with cystine urinary stones were treated by extracorporeal shock wave lithotripsy (Dormer HM-3) from December 1984 through October 1989. The average patient age was 35.2 years with a range of 14 to 59 years. Seventy per cent of these subjects had had previous open surgical operations for stones. The cases consisted of 7 ureteral stones and 37 renal stones, including 15 staghorn calculi. An average of 1.3 session of ESWL was carried out to treat ureteral stones. Thirty-seven renal units with renal stone required 96 sessions of lithotripsy (average 2.6 sessions per unit). Seven patients with ureteral stones required auxiliary procedures, i.e., one transurethral lithotripsy (TUL), two percutaneous nephrostomies (PNS) and one open surgery. Thirty-seven renal stones, including staghorn calculi was treated by ESWL and auxiliary treatment of 21 TUL procedures, one PNS, 16 PNL procedures and one chemical chemolysis. Successful fragmentation (residual debris less than or equal to 4 mm) was achieved in 85.7% of ureteral stones, 90.9% of renal stones and 73.3% of staghorn calculi. The stone free rates of patients with ureteral stones, renal stones and staghorn calculi were 71.4%, 50.0% and 53.5%, respectively, at 3 months after ESWL. No serious complications were seen in this series. Fever above 38.5 degrees C was the most common complications (13.5%). Ureteral perforation was encountered once in TUL procedures. Transfusion and selective arterial embolization were needed for one case treated by PNL procedures. Although cystine stone is harder to be fragmented by ESWL than other stone composition, ESWL and endourology may be effective and safe procedures for cystine stone patients.(ABSTRACT TRUNCATED AT 250 WORDS)
1984年12月至1989年10月期间,30例胱氨酸尿石症患者(16例男性,14例女性)接受了体外冲击波碎石术(Dormer HM-3)治疗。患者平均年龄35.2岁,年龄范围为14至59岁。这些患者中有70%曾因结石接受过开放手术。病例包括7例输尿管结石和37例肾结石,其中有15例鹿角形结石。输尿管结石平均进行1.3次体外冲击波碎石术。37个有肾结石的肾单位需要进行96次碎石术(平均每个肾单位2.6次)。7例输尿管结石患者需要辅助治疗,即1例经尿道碎石术(TUL)、2例经皮肾造瘘术(PNS)和1例开放手术。37例肾结石,包括鹿角形结石,接受了体外冲击波碎石术及辅助治疗,其中21次经尿道碎石术、1次经皮肾造瘘术、16次经皮肾镜取石术(PNL)和1次化学溶解术。输尿管结石85.7%、肾结石90.9%、鹿角形结石73.3%实现了成功碎石(残余碎片小于或等于4毫米)。体外冲击波碎石术后3个月,输尿管结石、肾结石和鹿角形结石患者的结石清除率分别为71.4%、50.0%和53.5%。本系列未观察到严重并发症。体温高于38.5摄氏度是最常见的并发症(13.5%)。经尿道碎石术中发生1次输尿管穿孔。1例经皮肾镜取石术治疗的患者需要输血和选择性动脉栓塞。尽管胱氨酸结石比其他结石成分更难被体外冲击波碎石术击碎,但体外冲击波碎石术和腔内泌尿外科手术对胱氨酸结石患者可能是有效且安全的治疗方法。(摘要截短至250字)