轴突导向：迂回曲折的排斥与吸引。

Axon guidance: repulsion and attraction in roundabout ways.

机构信息

Department of Biological Chemistry, Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

出版信息

Curr Biol. 2010 May 11;20(9):R400-2. doi: 10.1016/j.cub.2010.03.036.

DOI:10.1016/j.cub.2010.03.036

PMID:20462479

Abstract

The secreted signal Slit and its three receptors, Robo1-3, regulate axon guidance in the Drosophila nervous system. Differences in expression and structure of Robo paralogs contribute to diversifying growth cone responses to a common ligand.

摘要

分泌信号 Slit 及其三个受体 Robo1-3 调节果蝇神经系统中的轴突导向。Robo 同源物在表达和结构上的差异有助于使生长锥对共同配体的反应多样化。