Servicio de Oncología Pediátrica, Hospital de Cruces, Plaza de Cruces, Baracaldo, Vizcaya, Spain.
Clin Transl Oncol. 2010 Apr;12(4):271-7. doi: 10.1007/s12094-010-0503-y.
Medulloblastoma is the most common infratentorial malignant tumour under 15 years of age. In recent protocols, the patients are stratified for treatment in standard risk or high risk, according to the clinical variables as age, localized or disseminated disease, degree of surgical resection and more recently expected biological behaviour based on retrospective and prospective studies of former samples analyzed. The objectives for future treatments are reduce morbidity without jeopardizing survival.
髓母细胞瘤是 15 岁以下最常见的后颅窝恶性肿瘤。在最近的方案中,根据临床变量(如年龄、局限性或播散性疾病、手术切除程度以及最近基于对以前分析的样本进行的回顾性和前瞻性研究的预期生物学行为),将患者分为标准风险或高风险进行治疗。未来治疗的目标是降低发病率而不危及生存。