Yang Biru, Chan Shirley K, Mohammad Naqi, Meyer Jeffrey A, Risser Jan, Chronister Karen J, Wolverton Marcia L, Arafat Raouf R, Hwang Lu-Yu
Houston Department of Health and Human Services, TX, USA.
AIDS Care. 2010 Jun;22(6):766-74. doi: 10.1080/09540120903431348.
This cross-sectional study aimed to evaluate the prevalence and predictive factors associated with late HIV diagnoses in Houston, Texas using surveillance data. Study subjects were Houston/Harris County residents, 13 years or older, diagnosed with HIV and reported to the Houston Department of Health and Human Services. Late HIV diagnosis was defined as an AIDS diagnosis within three months of an HIV diagnosis. Logistic regression was used to investigate the association between late HIV diagnoses and predictive factors. We found 31% of the study population had late HIV diagnoses. The Hispanic population, men, older individuals, heterosexuals, and those diagnosed in private facilities were more likely to receive late HIV diagnoses. Sensitivity analysis was conducted to evaluate the effect of time from HIV to AIDS diagnosis on the prevalence of a late diagnosis, and on the predictors of late diagnosis. The sensitivity analysis showed time affects prevalence, but not the odds ratios of the risk factors for late diagnosis. This finding suggests HIV prevention programs should specifically target these populations at risk for late HIV diagnosis to encourage frequent HIV testing.
这项横断面研究旨在利用监测数据评估德克萨斯州休斯顿市与艾滋病病毒(HIV)晚期诊断相关的患病率及预测因素。研究对象为休斯顿/哈里斯县13岁及以上、被诊断出感染HIV并向休斯顿卫生与公众服务部报告的居民。HIV晚期诊断定义为在HIV诊断后三个月内被诊断为艾滋病。采用逻辑回归分析来研究HIV晚期诊断与预测因素之间的关联。我们发现31%的研究人群存在HIV晚期诊断情况。西班牙裔人群、男性、年长者、异性恋者以及在私立医疗机构被诊断出感染HIV的人群更有可能被晚期诊断。进行了敏感性分析,以评估从HIV诊断到艾滋病诊断的时间对晚期诊断患病率以及晚期诊断预测因素的影响。敏感性分析表明时间会影响患病率,但不会影响晚期诊断风险因素的比值比。这一发现表明,HIV预防项目应特别针对这些有HIV晚期诊断风险的人群,以鼓励他们频繁进行HIV检测。