Global Robotics Institute, Florida Hospital - Celebration Health, 410 Celebration Place, Suite 200, Celebration, FL 34747, USA.
Expert Rev Anticancer Ther. 2010 May;10(5):747-54. doi: 10.1586/era.10.16.
With younger and healthier men being diagnosed and treated for localized prostate cancer, postradical prostatectomy erectile dysfunction has become an ever more important matter of debate. However, the lack of a standardized definition for potency and no consensus regarding the optimal instrument for assessing recovery of erectile function after prostatectomy makes comparison among different series extremely difficult. The potential morbidity associated with the open surgical approach has resulted in the search for less invasive surgical options. One such option is robot-assisted radical prostatectomy (RARP) performed with the da Vinci system. In this article we critically review the current outcomes on post-RALP potency rates worldwide and compare the available data with the gold standard open RRP series. A review of the literature was performed for all published manuscripts written in English, comparative and non-comparative, between 2000 and 2009 using the keywords 'robotic radical prostatectomy, 'robot-assisted radical prostatectomy', 'nerve sparing', 'cavernosal nerve' and 'potency outcomes', using the Medline database. Manuscripts were selected according to their relevance to the current topic (i.e., original articles, number of patients in the series and prospective data collection) and incorporated into this review. To date, many large series of RARP are mature enough and have demonstrated that potency outcomes are at least comparable to if not better than open RRP. However, there is still controversy on which form of surgical approach to the neurovascular bundles provides the best results. Prospective multi-institutional studies evaluating outcomes following different techniques need to be designed and results analyzed by an independent third party. Until then, careful patient selection and wise intraoperative clinical judgment should be made when performing nerve-sparing surgery.
随着越来越多年轻和健康的男性被诊断和治疗局限性前列腺癌,根治性前列腺切除术后勃起功能障碍已成为一个日益重要的争论点。然而,由于缺乏对勃起功能的标准化定义,以及对前列腺切除术后勃起功能恢复的最佳评估工具缺乏共识,使得不同系列之间的比较变得极其困难。开放式手术方法的潜在发病率导致人们寻求更具侵入性的手术选择。达芬奇机器人辅助前列腺根治术(RARP)是一种这样的选择。在本文中,我们批判性地回顾了全球范围内 RALP 后勃起功能的当前结果,并将可用数据与开放式 RRP 系列的金标准进行了比较。我们使用关键词“机器人辅助前列腺根治术”、“机器人辅助前列腺切除术”、“神经保留”、“海绵体神经”和“勃起功能结果”,对 2000 年至 2009 年期间发表的所有英文比较和非比较文献进行了综述,并使用 Medline 数据库进行了检索。根据与当前主题的相关性(即原始文章、系列中的患者数量和前瞻性数据收集)选择了论文,并将其纳入本综述。迄今为止,许多大型 RARP 系列已经足够成熟,并且已经证明勃起功能的结果至少与开放式 RRP 相当,如果不是更好的话。然而,关于哪种形式的血管神经束手术方法提供最佳结果仍存在争议。需要设计评估不同技术的前瞻性多机构研究,并由独立的第三方分析结果。在那之前,在进行神经保留手术时,应仔细选择患者,并在术中进行明智的临床判断。