Department of Neurology, Rambam Health Care Campus, Technion Faculty of Medicine, Haifa, Israel.
J Stroke Cerebrovasc Dis. 2010 Sep-Oct;19(5):376-81. doi: 10.1016/j.jstrokecerebrovasdis.2009.06.004. Epub 2010 May 15.
There are currently no comparative data about ethnic differences in ischemic stroke in Arab and Jewish populations.
Data on 727 consecutive Arab and Jewish patients of working age (<or=65 years) with stroke were compared for risk profile, etiology, subtyping, and immediate functional outcome.
The mean age was 59.4 +/- 8.2 years for the Jewish and 53.7 +/- 8.6 years for the Arab patients (P = .03). Higher prevalence of diabetes was found in the Arab patients after adjustment by age, sex, and main vascular risk factors (P < .0001). After adjustment, a higher prevalence of normal transesophageal echocardiography results in the Arab population was found. Small vessel disease-related strokes were significantly more frequent in the Arab patients, whereas large vessel disease-related strokes and strokes resulting from multiple causes were significantly more frequent in the Jewish patients. No correlations were found between the high prevalence of diabetes (or any other examined factor) and the predominance of small vessel disease-related strokes in the Arab patients and large vessel disease-related strokes in the Jewish patients. There was no difference found in treatment or outcome between the Arab and the Jewish patients.
There are substantial differences in the risk profiles and subtyping of strokes between Arab and Jewish patients of working age.
目前尚无关于阿拉伯和犹太人群体缺血性脑卒中的种族差异的比较数据。
比较了 727 例连续的、年龄在工作年龄段(<65 岁)的阿拉伯和犹太脑卒中患者的风险状况、病因、亚型和即刻功能结局。
与犹太患者(59.4±8.2 岁)相比,阿拉伯患者的平均年龄为 53.7±8.6 岁(P=0.03)。校正年龄、性别和主要血管危险因素后,发现阿拉伯患者的糖尿病患病率更高(P<0.0001)。校正后发现,阿拉伯人群正常经食管超声心动图结果的患病率更高。小血管疾病相关脑卒中在阿拉伯患者中明显更常见,而大血管疾病相关脑卒中以及多病因引起的脑卒中在犹太患者中明显更常见。在阿拉伯患者中,糖尿病(或任何其他检查因素)的高患病率与小血管疾病相关脑卒中的盛行率之间,以及在犹太患者中,大血管疾病相关脑卒中与糖尿病(或任何其他检查因素)的高患病率与大血管疾病相关脑卒中之间均无相关性。阿拉伯患者和犹太患者在治疗或结局方面没有差异。
在工作年龄段的阿拉伯和犹太患者中,脑卒中的风险状况和亚型存在显著差异。